Molecular Mechanisms in Amyotrophic Lateral Sclerosis: The Role of Angiogenin, a Secreted RNase

Molecular Mechanisms in Amyotrophic Lateral Sclerosis: The Role of Angiogenin, a Secreted RNase

Amyotrophic lateral sclerosis is a fatal neurodegenerative disease caused by the loss of motoneurons. The precise molecular and cellular basis for neuronal death is not yet well established, but the contemporary view is that it is a culmination of multiple aberrant biological processes. Among the pr...

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Bibliographic Details
Main Authors: Isabela M. Aparicio-Erriu, Jochen ePrehn
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Neuroscience
Subjects:
Amyotrophic Lateral Sclerosis
RNA metabolism
stress signals
RNA binding proteins
Angiogenin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2012.00167/full

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