EPILEPSY AND PINEAL HORMONE: CURRENT STATE OF THE PROBLEM
The pineal gland hormone melatonin is the main regulator of biological rhythms. It affects sleep, brain bioelectric activity and seizures. The majority of experimental and clinical studies are confirmed the anticonvulsant properties of melatonin. However, in the scientific literature there is no dat...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
IRBIS LLC
2016-08-01
|
| Series: | Эпилепсия и пароксизмальные состояния |
| Subjects: | |
| Online Access: | https://www.epilepsia.su/jour/article/view/234 |
| _version_ | 1797879421323968512 |
|---|---|
| author | O. M. Oleynikova E. N. Kareva M. A. Bogomazova G. G. Avakyan Yu. V. Lagutin G. N. Avakyan |
| author_facet | O. M. Oleynikova E. N. Kareva M. A. Bogomazova G. G. Avakyan Yu. V. Lagutin G. N. Avakyan |
| author_sort | O. M. Oleynikova |
| collection | DOAJ |
| description | The pineal gland hormone melatonin is the main regulator of biological rhythms. It affects sleep, brain bioelectric activity and seizures. The majority of experimental and clinical studies are confirmed the anticonvulsant properties of melatonin. However, in the scientific literature there is no data on the concentration of melatonin in adult patients with epilepsy and epileptic syndromes. Thus study of melatonin in adult patients was developed. The evening (1 hour before bedtime), night concentrations (morning), and excretion of melatonin in 54 patients with focal symptomatic epilepsy at the age of 21 to 47 years were evaluated. It was found that seizures provoke a decrease of melatonin concentration. |
| first_indexed | 2024-04-10T02:47:21Z |
| format | Article |
| id | doaj.art-045568d06b384d328f083fffaa1c6da5 |
| institution | Directory Open Access Journal |
| issn | 2077-8333 2311-4088 |
| language | Russian |
| last_indexed | 2024-04-10T02:47:21Z |
| publishDate | 2016-08-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Эпилепсия и пароксизмальные состояния |
| spelling | doaj.art-045568d06b384d328f083fffaa1c6da52023-03-13T07:44:15ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882016-08-01342227233EPILEPSY AND PINEAL HORMONE: CURRENT STATE OF THE PROBLEMO. M. Oleynikova0E. N. Kareva1M. A. Bogomazova2G. G. Avakyan3Yu. V. Lagutin4G. N. Avakyan5SBEI HPE «RNSMU named after N.I. Pirogov» Ministry of Healthcare and Social Development of RussiaSBEI HPE «RNSMU named after N.I. Pirogov» Ministry of Healthcare and Social Development of RussiaSBEI HPE «RNSMU named after N.I. Pirogov» Ministry of Healthcare and Social Development of RussiaSBEI HPE «RNSMU named after N.I. Pirogov» Ministry of Healthcare and Social Development of RussiaSBEI HPE «RNSMU named after N.I. Pirogov» Ministry of Healthcare and Social Development of RussiaSBEI HPE «RNSMU named after N.I. Pirogov» Ministry of Healthcare and Social Development of RussiaThe pineal gland hormone melatonin is the main regulator of biological rhythms. It affects sleep, brain bioelectric activity and seizures. The majority of experimental and clinical studies are confirmed the anticonvulsant properties of melatonin. However, in the scientific literature there is no data on the concentration of melatonin in adult patients with epilepsy and epileptic syndromes. Thus study of melatonin in adult patients was developed. The evening (1 hour before bedtime), night concentrations (morning), and excretion of melatonin in 54 patients with focal symptomatic epilepsy at the age of 21 to 47 years were evaluated. It was found that seizures provoke a decrease of melatonin concentration.https://www.epilepsia.su/jour/article/view/234melatoninepilepsycircadian rhythm |
| spellingShingle | O. M. Oleynikova E. N. Kareva M. A. Bogomazova G. G. Avakyan Yu. V. Lagutin G. N. Avakyan EPILEPSY AND PINEAL HORMONE: CURRENT STATE OF THE PROBLEM Эпилепсия и пароксизмальные состояния melatonin epilepsy circadian rhythm |
| title | EPILEPSY AND PINEAL HORMONE: CURRENT STATE OF THE PROBLEM |
| title_full | EPILEPSY AND PINEAL HORMONE: CURRENT STATE OF THE PROBLEM |
| title_fullStr | EPILEPSY AND PINEAL HORMONE: CURRENT STATE OF THE PROBLEM |
| title_full_unstemmed | EPILEPSY AND PINEAL HORMONE: CURRENT STATE OF THE PROBLEM |
| title_short | EPILEPSY AND PINEAL HORMONE: CURRENT STATE OF THE PROBLEM |
| title_sort | epilepsy and pineal hormone current state of the problem |
| topic | melatonin epilepsy circadian rhythm |
| url | https://www.epilepsia.su/jour/article/view/234 |
| work_keys_str_mv | AT omoleynikova epilepsyandpinealhormonecurrentstateoftheproblem AT enkareva epilepsyandpinealhormonecurrentstateoftheproblem AT mabogomazova epilepsyandpinealhormonecurrentstateoftheproblem AT ggavakyan epilepsyandpinealhormonecurrentstateoftheproblem AT yuvlagutin epilepsyandpinealhormonecurrentstateoftheproblem AT gnavakyan epilepsyandpinealhormonecurrentstateoftheproblem |