Dopamine response gene pathways in dorsal striatum MSNs from a gene expression viewpoint: cAMP-mediated gene networks

Dopamine response gene pathways in dorsal striatum MSNs from a gene expression viewpoint: cAMP-mediated gene networks

Abstract Background Medium spiny neurons (MSNs) comprise the main body (95% in mouse) of the dorsal striatum neurons and represent dopaminoceptive GABAergic neurons. The cAMP (cyclic Adenosine MonoPhosphate)—mediated cascade of excitation and inhibition responses observed in MSN intracellular signal...

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Bibliographic Details
Main Authors: Vladimir N. Babenko, Anna G. Galyamina, Igor B. Rogozin, Dmitry A. Smagin, Natalia N. Kudryavtseva
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Neuroscience
Subjects:
Dorsal striatum
Mouse model of chronic social conflicts
DARPP-32
Alternative splicing
RNA-seq
Online Access:http://link.springer.com/article/10.1186/s12868-020-00560-w

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