Probing the conformational changes of in vivo overexpressed cell cycle regulator 6S ncRNA

The non-coding 6S RNA is a master regulator of the cell cycle in bacteria which binds to the RNA polymerase-σ70 holoenzyme during the stationary phase to inhibit transcription from the primary σ factor. Inhibition is reversed upon outgrowth from the stationary phase by synthesis of small product RNA...

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Bibliographic Details
Main Authors: Eleni Makraki, Sophia Miliara, Michalis Pagkalos, Michael Kokkinidis, Efstratios Mylonas, Vasiliki E. Fadouloglou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1219668/full