Computational Prediction of Resistance Induced Alanine-Mutation in ATP Site of Epidermal Growth Factor Receptor

Computational Prediction of Resistance Induced Alanine-Mutation in ATP Site of Epidermal Growth Factor Receptor

Epidermal growth factor receptor (EGFR) resistance to tyrosine kinase inhibitors can cause low survival rates in mutation-positive non-small cell lung cancer patients. It is necessary to predict new mutations in the development of more potent EGFR inhibitors since classical and rare mutations observ...

Full description

Bibliographic Details
Main Authors: Tasia Amelia, Aderian Novito Setiawan, Rahmana Emran Kartasasmita, Tomohiko Ohwada, Daryono Hadi Tjahjono
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
EGFR
erlotinib
mutation
prediction
resistance
Online Access:https://www.mdpi.com/1422-0067/23/24/15828

Internet

https://www.mdpi.com/1422-0067/23/24/15828

Similar Items