Anti-inflammatory and anti-microbial activities of aqueous leaves extract of Butea frondosa
Introduction: Butea frondosa has been suggested to be very useful in treating inflammatory diseases but no scientific investigation has been done in such direction. In this study the anti-inflammatory and anti-microbial activities of leaves aqueous extract of B. frondosa were determined in infected...
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| Format: | Article |
| Language: | English |
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Shahrekord University of Medical Sciences
2016-03-01
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| Series: | Journal of HerbMed Pharmacology |
| Subjects: | |
| Online Access: | http://herbmedpharmacol.com/PDF/JHP_1011_20151215132227 |
| _version_ | 1818871275058102272 |
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| author | Amit Gupta Sushama R Chaphalkar |
| author_facet | Amit Gupta Sushama R Chaphalkar |
| author_sort | Amit Gupta |
| collection | DOAJ |
| description | Introduction: Butea frondosa has been suggested to be very useful in treating inflammatory diseases but no scientific investigation has been done in such direction. In this study the anti-inflammatory and anti-microbial activities of leaves aqueous extract of B. frondosa were determined in infected and non-infected human whole blood against specific vaccine antigen, HBsAg.Methods: In order to explore the anti-inflammatory and anti-microbial activities of B. frondosa (0.5–0 mg/mL; 50 μl), infected (virally) and non infected (control) human whole blood samples were stimulated with hepatitis B vaccine containing surface antigen (HBsAg, 20 μg/mL;10 μl) in order to determined its blood counts and proliferation assay.Results: Aqueous leaves extract of B. frondosa (10 mg/mL; 50 μl) containing HBsAg inhibited the percentage count of monocytes as well as granulocytes population in both cases. In addition, this aqueous extract also reduced its proliferation rate at higher doses.Conclusion: Aqueous leaves extract of B. frondosa possesses both anti-inflammatory and antimicrobial activities and might be used for these purposes. |
| first_indexed | 2024-12-19T12:20:19Z |
| format | Article |
| id | doaj.art-045a871fd2ca425395babf7b29deac2f |
| institution | Directory Open Access Journal |
| issn | 2345-5004 |
| language | English |
| last_indexed | 2024-12-19T12:20:19Z |
| publishDate | 2016-03-01 |
| publisher | Shahrekord University of Medical Sciences |
| record_format | Article |
| series | Journal of HerbMed Pharmacology |
| spelling | doaj.art-045a871fd2ca425395babf7b29deac2f2022-12-21T20:21:48ZengShahrekord University of Medical SciencesJournal of HerbMed Pharmacology2345-50042016-03-01528588JHP_1011_20151215132227Anti-inflammatory and anti-microbial activities of aqueous leaves extract of Butea frondosaAmit Gupta0Sushama R Chaphalkar1Vidya Pratishthan’s School of Biotechnology (Research centre affiliated to Savitribai Phule Pune University), Baramati, District Pune, Maharashtra, IndiaVidya Pratishthan’s School of Biotechnology (Research centre affiliated to Savitribai Phule Pune University), Baramati, District Pune, Maharashtra, IndiaIntroduction: Butea frondosa has been suggested to be very useful in treating inflammatory diseases but no scientific investigation has been done in such direction. In this study the anti-inflammatory and anti-microbial activities of leaves aqueous extract of B. frondosa were determined in infected and non-infected human whole blood against specific vaccine antigen, HBsAg.Methods: In order to explore the anti-inflammatory and anti-microbial activities of B. frondosa (0.5–0 mg/mL; 50 μl), infected (virally) and non infected (control) human whole blood samples were stimulated with hepatitis B vaccine containing surface antigen (HBsAg, 20 μg/mL;10 μl) in order to determined its blood counts and proliferation assay.Results: Aqueous leaves extract of B. frondosa (10 mg/mL; 50 μl) containing HBsAg inhibited the percentage count of monocytes as well as granulocytes population in both cases. In addition, this aqueous extract also reduced its proliferation rate at higher doses.Conclusion: Aqueous leaves extract of B. frondosa possesses both anti-inflammatory and antimicrobial activities and might be used for these purposes.http://herbmedpharmacol.com/PDF/JHP_1011_20151215132227Butea frondosaAnti-inflammatoryAnti-microbialHepatitis B vaccine |
| spellingShingle | Amit Gupta Sushama R Chaphalkar Anti-inflammatory and anti-microbial activities of aqueous leaves extract of Butea frondosa Journal of HerbMed Pharmacology Butea frondosa Anti-inflammatory Anti-microbial Hepatitis B vaccine |
| title | Anti-inflammatory and anti-microbial activities of aqueous leaves extract of Butea frondosa |
| title_full | Anti-inflammatory and anti-microbial activities of aqueous leaves extract of Butea frondosa |
| title_fullStr | Anti-inflammatory and anti-microbial activities of aqueous leaves extract of Butea frondosa |
| title_full_unstemmed | Anti-inflammatory and anti-microbial activities of aqueous leaves extract of Butea frondosa |
| title_short | Anti-inflammatory and anti-microbial activities of aqueous leaves extract of Butea frondosa |
| title_sort | anti inflammatory and anti microbial activities of aqueous leaves extract of butea frondosa |
| topic | Butea frondosa Anti-inflammatory Anti-microbial Hepatitis B vaccine |
| url | http://herbmedpharmacol.com/PDF/JHP_1011_20151215132227 |
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