Advancements in tissue and organ 3D bioprinting: Current techniques, applications, and future perspectives
3D bioprinting techniques have emerged as a flexible tool in tissue engineering and regenerative medicine to fabricate or pattern functional 3D bio-structures with precise geometric designs, bridging the divergence between engineered and natural tissue constructs. A significantly increasing developm...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-04-01
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| Series: | Materials & Design |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0264127524002260 |
| _version_ | 1797214933498200064 |
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| author | Mojdeh Mirshafiei Hamid Rashedi Fatemeh Yazdian Abbas Rahdar Francesco Baino |
| author_facet | Mojdeh Mirshafiei Hamid Rashedi Fatemeh Yazdian Abbas Rahdar Francesco Baino |
| author_sort | Mojdeh Mirshafiei |
| collection | DOAJ |
| description | 3D bioprinting techniques have emerged as a flexible tool in tissue engineering and regenerative medicine to fabricate or pattern functional 3D bio-structures with precise geometric designs, bridging the divergence between engineered and natural tissue constructs. A significantly increasing development has been achieved in understanding the relationship between the 3D-printing process and the structures, properties, and applications of the objects created. The ongoing advancement of novel biomaterial inks has enabled manufacturing of models and in vitro implants capable of achieving some level of success in preclinical trials. Remarkable progress in cell biology and biology-inspired computational design has assisted in achieving the latest milestone with planned tissue- or organ-like constructs having specific levels of functionality. However, biofabricated constructs still have a long way to go before reaching clinics. This review presents a picture of 3D bioprinting in the context of tissue engineering and regenerative medicine, with focus on biomaterials-related and design-centred aspects. Biomedical applications are described in detail in relation to major tissues or organs considered in the human body. Current technical limitations, challenges, future prospects and improvements are critically outlined and discussed. |
| first_indexed | 2024-04-24T11:22:03Z |
| format | Article |
| id | doaj.art-045ae1df42ba4ca5b14de7ad634da5d9 |
| institution | Directory Open Access Journal |
| issn | 0264-1275 |
| language | English |
| last_indexed | 2024-04-24T11:22:03Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Materials & Design |
| spelling | doaj.art-045ae1df42ba4ca5b14de7ad634da5d92024-04-11T04:40:44ZengElsevierMaterials & Design0264-12752024-04-01240112853Advancements in tissue and organ 3D bioprinting: Current techniques, applications, and future perspectivesMojdeh Mirshafiei0Hamid Rashedi1Fatemeh Yazdian2Abbas Rahdar3Francesco Baino4Department of Biotechnology, School of Chemical Engineering, College of Engineering, University of Tehran, Tehran, IranDepartment of Biotechnology, School of Chemical Engineering, College of Engineering, University of Tehran, Tehran, IranDepartment of Life Science Engineering, Faculty of New Science and Technologies, University of Tehran, Tehran, Iran; Corresponding authors.Department of Physics, School of Basic Sciences, University of Zabol, Zabol, Iran; Corresponding authors.Institute of Materials Physics and Engineering, Department of Applied Science and Technology, Politecnico di Torino, Torino, Italy; Corresponding authors.3D bioprinting techniques have emerged as a flexible tool in tissue engineering and regenerative medicine to fabricate or pattern functional 3D bio-structures with precise geometric designs, bridging the divergence between engineered and natural tissue constructs. A significantly increasing development has been achieved in understanding the relationship between the 3D-printing process and the structures, properties, and applications of the objects created. The ongoing advancement of novel biomaterial inks has enabled manufacturing of models and in vitro implants capable of achieving some level of success in preclinical trials. Remarkable progress in cell biology and biology-inspired computational design has assisted in achieving the latest milestone with planned tissue- or organ-like constructs having specific levels of functionality. However, biofabricated constructs still have a long way to go before reaching clinics. This review presents a picture of 3D bioprinting in the context of tissue engineering and regenerative medicine, with focus on biomaterials-related and design-centred aspects. Biomedical applications are described in detail in relation to major tissues or organs considered in the human body. Current technical limitations, challenges, future prospects and improvements are critically outlined and discussed.http://www.sciencedirect.com/science/article/pii/S0264127524002260Additive manufacturingBioprintingBiomaterialsBioinkTissue engineering |
| spellingShingle | Mojdeh Mirshafiei Hamid Rashedi Fatemeh Yazdian Abbas Rahdar Francesco Baino Advancements in tissue and organ 3D bioprinting: Current techniques, applications, and future perspectives Materials & Design Additive manufacturing Bioprinting Biomaterials Bioink Tissue engineering |
| title | Advancements in tissue and organ 3D bioprinting: Current techniques, applications, and future perspectives |
| title_full | Advancements in tissue and organ 3D bioprinting: Current techniques, applications, and future perspectives |
| title_fullStr | Advancements in tissue and organ 3D bioprinting: Current techniques, applications, and future perspectives |
| title_full_unstemmed | Advancements in tissue and organ 3D bioprinting: Current techniques, applications, and future perspectives |
| title_short | Advancements in tissue and organ 3D bioprinting: Current techniques, applications, and future perspectives |
| title_sort | advancements in tissue and organ 3d bioprinting current techniques applications and future perspectives |
| topic | Additive manufacturing Bioprinting Biomaterials Bioink Tissue engineering |
| url | http://www.sciencedirect.com/science/article/pii/S0264127524002260 |
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