Micelle Encapsulation of Ferromagnetic Nanoparticles of Iron Carbide@Iron Oxide in Chitosan as Possible Nanomedicine Agent
In this work, the synthesis and characterization of core/shell nanoparticles of iron carbide@iron oxide (Fe<sub>3</sub>C/γ-Fe<sub>2</sub>O<sub>3</sub>) encapsulated into micelles of sodium dodecylsulfate and oleic acid and stabilized with chitosan was developed. T...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-05-01
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| Series: | Colloids and Interfaces |
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| Online Access: | https://www.mdpi.com/2504-5377/4/2/22 |
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| author | Perla Yazmin Sauceda-Oloño Hector Cardenas-Sanchez Anya Isabel Argüelles-Pesqueira Cindy Gutierrez-Valenzuela Mario Enrique Alvarez-Ramos Armando Lucero-Acuña Paul Zavala-Rivera |
| author_facet | Perla Yazmin Sauceda-Oloño Hector Cardenas-Sanchez Anya Isabel Argüelles-Pesqueira Cindy Gutierrez-Valenzuela Mario Enrique Alvarez-Ramos Armando Lucero-Acuña Paul Zavala-Rivera |
| author_sort | Perla Yazmin Sauceda-Oloño |
| collection | DOAJ |
| description | In this work, the synthesis and characterization of core/shell nanoparticles of iron carbide@iron oxide (Fe<sub>3</sub>C/γ-Fe<sub>2</sub>O<sub>3</sub>) encapsulated into micelles of sodium dodecylsulfate and oleic acid and stabilized with chitosan was developed. The materials were sonosynthesized at low intensities using standard ultrasonic baths with iron pentacarbonyl (Fe(CO)<sub>5</sub>) and oleic acid as iron source and hydrophobic stabilizer, respectively; obtaining nanoparticles with a hydrodynamic diameter of 19.71 nm and polydispersive index (PDI) of 0.13. The iron carbide@iron oxide nanoparticles (ICIONPs) in oleic acid were used as the organic phase during the self-assemble of nanoemulsion with sodium dodecylsulfate in water to obtain the metastable micelles. The final step involved the stabilization of the micelles using low molecular weight chitosan solution at 2% in acetic acid by ultrasonication bath. The nanosystem showed a hydrodynamic diameter of 185.30 nm, a PDI of 0.15 with a superficial charge ζ of 36.70 mV. Due to the magnetic, physical and chemical properties previously measured of the ICIONPs, it is believed that this type of nanoparticles can be used as a possible nanomedicine agent. |
| first_indexed | 2024-03-10T19:38:16Z |
| format | Article |
| id | doaj.art-045b1f7750114905ac25a6cbc08e71d6 |
| institution | Directory Open Access Journal |
| issn | 2504-5377 |
| language | English |
| last_indexed | 2024-03-10T19:38:16Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Colloids and Interfaces |
| spelling | doaj.art-045b1f7750114905ac25a6cbc08e71d62023-11-20T01:25:51ZengMDPI AGColloids and Interfaces2504-53772020-05-01422210.3390/colloids4020022Micelle Encapsulation of Ferromagnetic Nanoparticles of Iron Carbide@Iron Oxide in Chitosan as Possible Nanomedicine AgentPerla Yazmin Sauceda-Oloño0Hector Cardenas-Sanchez1Anya Isabel Argüelles-Pesqueira2Cindy Gutierrez-Valenzuela3Mario Enrique Alvarez-Ramos4Armando Lucero-Acuña5Paul Zavala-Rivera6Posgrado en Nanotecnología, Departamento de Física, Universidad de Sonora, Hermosillo 83000, MexicoDepartamento de Ingeniería Química y Metalurgia, Universidad de Sonora, Hermosillo 83000, MexicoDepartamento de Ingeniería Química y Metalurgia, Universidad de Sonora, Hermosillo 83000, MexicoDepartamento de Ingeniería Química y Metalurgia, Universidad de Sonora, Hermosillo 83000, MexicoPosgrado en Nanotecnología, Departamento de Física, Universidad de Sonora, Hermosillo 83000, MexicoPosgrado en Nanotecnología, Departamento de Física, Universidad de Sonora, Hermosillo 83000, MexicoPosgrado en Nanotecnología, Departamento de Física, Universidad de Sonora, Hermosillo 83000, MexicoIn this work, the synthesis and characterization of core/shell nanoparticles of iron carbide@iron oxide (Fe<sub>3</sub>C/γ-Fe<sub>2</sub>O<sub>3</sub>) encapsulated into micelles of sodium dodecylsulfate and oleic acid and stabilized with chitosan was developed. The materials were sonosynthesized at low intensities using standard ultrasonic baths with iron pentacarbonyl (Fe(CO)<sub>5</sub>) and oleic acid as iron source and hydrophobic stabilizer, respectively; obtaining nanoparticles with a hydrodynamic diameter of 19.71 nm and polydispersive index (PDI) of 0.13. The iron carbide@iron oxide nanoparticles (ICIONPs) in oleic acid were used as the organic phase during the self-assemble of nanoemulsion with sodium dodecylsulfate in water to obtain the metastable micelles. The final step involved the stabilization of the micelles using low molecular weight chitosan solution at 2% in acetic acid by ultrasonication bath. The nanosystem showed a hydrodynamic diameter of 185.30 nm, a PDI of 0.15 with a superficial charge ζ of 36.70 mV. Due to the magnetic, physical and chemical properties previously measured of the ICIONPs, it is believed that this type of nanoparticles can be used as a possible nanomedicine agent.https://www.mdpi.com/2504-5377/4/2/22nanocapsulesiron carbideiron oxidechitosan |
| spellingShingle | Perla Yazmin Sauceda-Oloño Hector Cardenas-Sanchez Anya Isabel Argüelles-Pesqueira Cindy Gutierrez-Valenzuela Mario Enrique Alvarez-Ramos Armando Lucero-Acuña Paul Zavala-Rivera Micelle Encapsulation of Ferromagnetic Nanoparticles of Iron Carbide@Iron Oxide in Chitosan as Possible Nanomedicine Agent Colloids and Interfaces nanocapsules iron carbide iron oxide chitosan |
| title | Micelle Encapsulation of Ferromagnetic Nanoparticles of Iron Carbide@Iron Oxide in Chitosan as Possible Nanomedicine Agent |
| title_full | Micelle Encapsulation of Ferromagnetic Nanoparticles of Iron Carbide@Iron Oxide in Chitosan as Possible Nanomedicine Agent |
| title_fullStr | Micelle Encapsulation of Ferromagnetic Nanoparticles of Iron Carbide@Iron Oxide in Chitosan as Possible Nanomedicine Agent |
| title_full_unstemmed | Micelle Encapsulation of Ferromagnetic Nanoparticles of Iron Carbide@Iron Oxide in Chitosan as Possible Nanomedicine Agent |
| title_short | Micelle Encapsulation of Ferromagnetic Nanoparticles of Iron Carbide@Iron Oxide in Chitosan as Possible Nanomedicine Agent |
| title_sort | micelle encapsulation of ferromagnetic nanoparticles of iron carbide iron oxide in chitosan as possible nanomedicine agent |
| topic | nanocapsules iron carbide iron oxide chitosan |
| url | https://www.mdpi.com/2504-5377/4/2/22 |
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