Simultaneous trimodal single-cell measurement of transcripts, epitopes, and chromatin accessibility using TEA-seq

Simultaneous trimodal single-cell measurement of transcripts, epitopes, and chromatin accessibility using TEA-seq

Single-cell measurements of cellular characteristics have been instrumental in understanding the heterogeneous pathways that drive differentiation, cellular responses to signals, and human disease. Recent advances have allowed paired capture of protein abundance and transcriptomic state, but a lack...

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Bibliographic Details
Main Authors: Elliott Swanson, Cara Lord, Julian Reading, Alexander T Heubeck, Palak C Genge, Zachary Thomson, Morgan DA Weiss, Xiao-jun Li, Adam K Savage, Richard R Green, Troy R Torgerson, Thomas F Bumol, Lucas T Graybuck, Peter J Skene
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
transcription
chromatin
epitopes
sequencing
genomics
multiomics
Online Access:https://elifesciences.org/articles/63632

Internet

https://elifesciences.org/articles/63632

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