Evaluation of the training program for p16/ Ki-67 dual immunocytochemical staining interpretation for laboratory staff without experience in cervical cytology and immunocytochemistry

p16/Ki-67 dual immunocytochemical staining (DS) is considered easy to interpret if evaluators are properly trained, however, there is no consensus on what constitutes proper training. In the present study we evaluated a protocol for teaching DS evaluation on students inexperienced in cervical cytolo...

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Main Authors: Prevodnik Veronika Kloboves, Marinsek Ziva Pohar, Zalar Janja, Rozina Hermina, Kotnik Nika, Jerman Tine, Varl Jerneja, Ivanus Urska
Format: Article
Language:English
Published: Sciendo 2020-03-01
Series:Radiology and Oncology
Subjects:
Online Access:https://doi.org/10.2478/raon-2020-0018
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author Prevodnik Veronika Kloboves
Marinsek Ziva Pohar
Zalar Janja
Rozina Hermina
Kotnik Nika
Jerman Tine
Varl Jerneja
Ivanus Urska
author_facet Prevodnik Veronika Kloboves
Marinsek Ziva Pohar
Zalar Janja
Rozina Hermina
Kotnik Nika
Jerman Tine
Varl Jerneja
Ivanus Urska
author_sort Prevodnik Veronika Kloboves
collection DOAJ
description p16/Ki-67 dual immunocytochemical staining (DS) is considered easy to interpret if evaluators are properly trained, however, there is no consensus on what constitutes proper training. In the present study we evaluated a protocol for teaching DS evaluation on students inexperienced in cervical cytology.
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spelling doaj.art-04651040e1d947f59f3dc2a93479af172022-12-21T21:27:45ZengSciendoRadiology and Oncology1581-32072020-03-0154220120810.2478/raon-2020-0018raon-2020-0018Evaluation of the training program for p16/ Ki-67 dual immunocytochemical staining interpretation for laboratory staff without experience in cervical cytology and immunocytochemistryPrevodnik Veronika Kloboves0Marinsek Ziva Pohar1Zalar Janja2Rozina Hermina3Kotnik Nika4Jerman Tine5Varl Jerneja6Ivanus Urska7Department of Cytopathology, Institute of Oncology Ljubljana, Ljubljana, SloveniaDepartment of Cytopathology, Institute of Oncology Ljubljana, Ljubljana, SloveniaDepartment of Cytopathology, Institute of Oncology Ljubljana, Ljubljana, SloveniaDepartment of Cytopathology, Institute of Oncology Ljubljana, Ljubljana, SloveniaDepartment of Experimental Allergology and Immunodermatology Oldenburg, Carl von Ossietzky Universität, Oldenburg, GermanyEpidemiology and Cancer Registry, Institute of Oncology Ljubljana, Ljubljana, SloveniaFaculty of Medicine, University of Ljubljana, Ljubljana, SloveniaEpidemiology and Cancer Registry, Institute of Oncology Ljubljana, Ljubljana, Sloveniap16/Ki-67 dual immunocytochemical staining (DS) is considered easy to interpret if evaluators are properly trained, however, there is no consensus on what constitutes proper training. In the present study we evaluated a protocol for teaching DS evaluation on students inexperienced in cervical cytology.https://doi.org/10.2478/raon-2020-0018training protocolp16/ki-67 dual immunocytochemical stainingagreementaccuracyinter-observer reproducibility
spellingShingle Prevodnik Veronika Kloboves
Marinsek Ziva Pohar
Zalar Janja
Rozina Hermina
Kotnik Nika
Jerman Tine
Varl Jerneja
Ivanus Urska
Evaluation of the training program for p16/ Ki-67 dual immunocytochemical staining interpretation for laboratory staff without experience in cervical cytology and immunocytochemistry
Radiology and Oncology
training protocol
p16/ki-67 dual immunocytochemical staining
agreement
accuracy
inter-observer reproducibility
title Evaluation of the training program for p16/ Ki-67 dual immunocytochemical staining interpretation for laboratory staff without experience in cervical cytology and immunocytochemistry
title_full Evaluation of the training program for p16/ Ki-67 dual immunocytochemical staining interpretation for laboratory staff without experience in cervical cytology and immunocytochemistry
title_fullStr Evaluation of the training program for p16/ Ki-67 dual immunocytochemical staining interpretation for laboratory staff without experience in cervical cytology and immunocytochemistry
title_full_unstemmed Evaluation of the training program for p16/ Ki-67 dual immunocytochemical staining interpretation for laboratory staff without experience in cervical cytology and immunocytochemistry
title_short Evaluation of the training program for p16/ Ki-67 dual immunocytochemical staining interpretation for laboratory staff without experience in cervical cytology and immunocytochemistry
title_sort evaluation of the training program for p16 ki 67 dual immunocytochemical staining interpretation for laboratory staff without experience in cervical cytology and immunocytochemistry
topic training protocol
p16/ki-67 dual immunocytochemical staining
agreement
accuracy
inter-observer reproducibility
url https://doi.org/10.2478/raon-2020-0018
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