Identification of PTPN22 as a potential genetic biomarker for abdominal aortic aneurysm

Identification of PTPN22 as a potential genetic biomarker for abdominal aortic aneurysm

Abdominal aortic aneurysm (AAA) is a severe life-threatening disease that is generally asymptomatic and is diagnosed at a very late stage. The genetic component underpinning AAA is considerable, with an estimated heritability of up to 70%. Therefore, identifying genetic biomarkers for AAA is valuabl...

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Bibliographic Details
Main Authors: Peng Ruan, Lei Gao, Hui Jiang, Tianshu Chu, Jianjun Ge, Xiang Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
abdominal aortic aneurysm
diagnosis
biomarker
PTPN22
cellular AAA model
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.1061771/full

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