Effect of administration of vitamins C and E on fertilization capacity of rats exposed to noise stress
The aims of this study were to evaluate the effects of administration of Vitamins C and E on fertilization capacity in rats exposed to noise stress. 40 adult male rats were randomly divided into 5 equal groups. Group 1 as controls who were not exposed to noise and groups 2-5 exposed to noise with 90...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Noise and Health |
| Subjects: | |
| Online Access: | http://www.noiseandhealth.org/article.asp?issn=1463-1741;year=2013;volume=15;issue=64;spage=194;epage=198;aulast=Saki |
| _version_ | 1828239133392240640 |
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| author | Ghasem Saki Majid Jasemi Ali Reza Sarkaki Ali Fathollahi |
| author_facet | Ghasem Saki Majid Jasemi Ali Reza Sarkaki Ali Fathollahi |
| author_sort | Ghasem Saki |
| collection | DOAJ |
| description | The aims of this study were to evaluate the effects of administration of Vitamins C and E on fertilization capacity in rats exposed to noise stress. 40 adult male rats were randomly divided into 5 equal groups. Group 1 as controls who were not exposed to noise and groups 2-5 exposed to noise with 90-120 dB intensity and 300-350 Hz frequency from 7 pm to 7 am everyday for 50 days. Group 2 exposed to noise and did not receive Vitamins. Group 3 received vitamin C, Group 4 received Vitamin E. Group 5 received Vitamins C and E concomitantly. After 50 days, serum Follicle-stimulating hormone (FSH), Luteinizing hormone (LH) and testosterone were calculated. Then each rat was left with three female rats for mating. Pregnant females were sacrificed on the 19 th day of pregnancy and evaluated for the presence and number of viable, dead and absorbed fetuses. The level of FSH, LH and testosterone significantly decreased in rats exposed to noise (P < 0.05). By administration of Vitamins in groups 3-5 we observed that the level of hormones significantly increased in compared to group 2 (P < 0.05). The fertilization capacity of male rats in groups 3-5 significantly increased in compared to group 2 (P < 0.05). There was significant difference between groups 1 and 2 in case of fertilization capacity (P = 0.001). The data in this study strongly suggests a negative role for noise stress on level of FSH, LH and testosterone level and also fertilization capacity of male rats. To complement the information it is suggested that this research be done on human samples. |
| first_indexed | 2024-04-12T21:16:39Z |
| format | Article |
| id | doaj.art-04666795e41b451588e47fc14b0d2b3a |
| institution | Directory Open Access Journal |
| issn | 1463-1741 1998-4030 |
| language | English |
| last_indexed | 2024-04-12T21:16:39Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Noise and Health |
| spelling | doaj.art-04666795e41b451588e47fc14b0d2b3a2022-12-22T03:16:24ZengWolters Kluwer Medknow PublicationsNoise and Health1463-17411998-40302013-01-01156419419810.4103/1463-1741.112374Effect of administration of vitamins C and E on fertilization capacity of rats exposed to noise stressGhasem SakiMajid JasemiAli Reza SarkakiAli FathollahiThe aims of this study were to evaluate the effects of administration of Vitamins C and E on fertilization capacity in rats exposed to noise stress. 40 adult male rats were randomly divided into 5 equal groups. Group 1 as controls who were not exposed to noise and groups 2-5 exposed to noise with 90-120 dB intensity and 300-350 Hz frequency from 7 pm to 7 am everyday for 50 days. Group 2 exposed to noise and did not receive Vitamins. Group 3 received vitamin C, Group 4 received Vitamin E. Group 5 received Vitamins C and E concomitantly. After 50 days, serum Follicle-stimulating hormone (FSH), Luteinizing hormone (LH) and testosterone were calculated. Then each rat was left with three female rats for mating. Pregnant females were sacrificed on the 19 th day of pregnancy and evaluated for the presence and number of viable, dead and absorbed fetuses. The level of FSH, LH and testosterone significantly decreased in rats exposed to noise (P < 0.05). By administration of Vitamins in groups 3-5 we observed that the level of hormones significantly increased in compared to group 2 (P < 0.05). The fertilization capacity of male rats in groups 3-5 significantly increased in compared to group 2 (P < 0.05). There was significant difference between groups 1 and 2 in case of fertilization capacity (P = 0.001). The data in this study strongly suggests a negative role for noise stress on level of FSH, LH and testosterone level and also fertilization capacity of male rats. To complement the information it is suggested that this research be done on human samples.http://www.noiseandhealth.org/article.asp?issn=1463-1741;year=2013;volume=15;issue=64;spage=194;epage=198;aulast=SakiAntioxidantsinfertilitymortalitypregnancy |
| spellingShingle | Ghasem Saki Majid Jasemi Ali Reza Sarkaki Ali Fathollahi Effect of administration of vitamins C and E on fertilization capacity of rats exposed to noise stress Noise and Health Antioxidants infertility mortality pregnancy |
| title | Effect of administration of vitamins C and E on fertilization capacity of rats exposed to noise stress |
| title_full | Effect of administration of vitamins C and E on fertilization capacity of rats exposed to noise stress |
| title_fullStr | Effect of administration of vitamins C and E on fertilization capacity of rats exposed to noise stress |
| title_full_unstemmed | Effect of administration of vitamins C and E on fertilization capacity of rats exposed to noise stress |
| title_short | Effect of administration of vitamins C and E on fertilization capacity of rats exposed to noise stress |
| title_sort | effect of administration of vitamins c and e on fertilization capacity of rats exposed to noise stress |
| topic | Antioxidants infertility mortality pregnancy |
| url | http://www.noiseandhealth.org/article.asp?issn=1463-1741;year=2013;volume=15;issue=64;spage=194;epage=198;aulast=Saki |
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