Clinical Impact of Sarcopenia on Gastrointestinal Tumors

Preoperative risk stratification in cancer surgery is important to improve treatment and outcome. Sarcopenia is defined by progressive and generalized loss of skeletal muscle mass and strength and is now getting attention as a poor prognostic factor. The purpose of this review was to explore the imp...

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Main Authors: Ana Pereira, Joaquim Costa Pereira, Sandra F. Martins
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Gastrointestinal Disorders
Subjects:
Online Access:https://www.mdpi.com/2624-5647/3/1/6
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author Ana Pereira
Joaquim Costa Pereira
Sandra F. Martins
author_facet Ana Pereira
Joaquim Costa Pereira
Sandra F. Martins
author_sort Ana Pereira
collection DOAJ
description Preoperative risk stratification in cancer surgery is important to improve treatment and outcome. Sarcopenia is defined by progressive and generalized loss of skeletal muscle mass and strength and is now getting attention as a poor prognostic factor. The purpose of this review was to explore the impact of sarcopenia on short and long-term outcomes in patients undergoing surgical resection of gastrointestinal tumors. Recent studies suggest that sarcopenia contributes to postoperative complications and overall survival. The relatively simple evaluability, as well as its modifiable nature, provides an intriguing potential for sarcopenia to be included in standard preoperative clinical evaluation. Such evaluations can provide physicians with important information to target high-risk individuals with prophylactic measures and eventually improve surgical outcomes.
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spelling doaj.art-04684e10198241779c7cc4dd454808372023-11-21T11:35:40ZengMDPI AGGastrointestinal Disorders2624-56472021-03-0131516010.3390/gidisord3010006Clinical Impact of Sarcopenia on Gastrointestinal TumorsAna Pereira0Joaquim Costa Pereira1Sandra F. Martins2Surgery Resident, Braga Hospital, 4710-243 Braga, PortugalColoproctology Unit, Surgery Department, Braga Hospital, 4710-243 Braga, PortugalColoproctology Unit, Surgery Department, Braga Hospital, 4710-243 Braga, PortugalPreoperative risk stratification in cancer surgery is important to improve treatment and outcome. Sarcopenia is defined by progressive and generalized loss of skeletal muscle mass and strength and is now getting attention as a poor prognostic factor. The purpose of this review was to explore the impact of sarcopenia on short and long-term outcomes in patients undergoing surgical resection of gastrointestinal tumors. Recent studies suggest that sarcopenia contributes to postoperative complications and overall survival. The relatively simple evaluability, as well as its modifiable nature, provides an intriguing potential for sarcopenia to be included in standard preoperative clinical evaluation. Such evaluations can provide physicians with important information to target high-risk individuals with prophylactic measures and eventually improve surgical outcomes.https://www.mdpi.com/2624-5647/3/1/6gastrointestinal tumorsmorbimortalitysarcopenia
spellingShingle Ana Pereira
Joaquim Costa Pereira
Sandra F. Martins
Clinical Impact of Sarcopenia on Gastrointestinal Tumors
Gastrointestinal Disorders
gastrointestinal tumors
morbimortality
sarcopenia
title Clinical Impact of Sarcopenia on Gastrointestinal Tumors
title_full Clinical Impact of Sarcopenia on Gastrointestinal Tumors
title_fullStr Clinical Impact of Sarcopenia on Gastrointestinal Tumors
title_full_unstemmed Clinical Impact of Sarcopenia on Gastrointestinal Tumors
title_short Clinical Impact of Sarcopenia on Gastrointestinal Tumors
title_sort clinical impact of sarcopenia on gastrointestinal tumors
topic gastrointestinal tumors
morbimortality
sarcopenia
url https://www.mdpi.com/2624-5647/3/1/6
work_keys_str_mv AT anapereira clinicalimpactofsarcopeniaongastrointestinaltumors
AT joaquimcostapereira clinicalimpactofsarcopeniaongastrointestinaltumors
AT sandrafmartins clinicalimpactofsarcopeniaongastrointestinaltumors