Association between dietary inflammatory index and mental disorders using multilevel modeling with GLIMMIX
IntroductionThe Dietary Inflammatory Index (DII) is a composite nutritional index that has gained significant attention in the past decade due to its association with physical and mental well-being. To accurately assess the precise effects of DII on health outcomes, the effects of nutrients and food...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-01-01
|
| Series: | Frontiers in Nutrition |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2024.1288793/full |
| _version_ | 1827383140241375232 |
|---|---|
| author | Reza Beiranvand Mohammad Ali Mansournia Farhad Vahid Ali-Akbar Nejatisafa Saharnaz Nedjat |
| author_facet | Reza Beiranvand Mohammad Ali Mansournia Farhad Vahid Ali-Akbar Nejatisafa Saharnaz Nedjat |
| author_sort | Reza Beiranvand |
| collection | DOAJ |
| description | IntroductionThe Dietary Inflammatory Index (DII) is a composite nutritional index that has gained significant attention in the past decade due to its association with physical and mental well-being. To accurately assess the precise effects of DII on health outcomes, the effects of nutrients and foods need to be adjusted. This study aimed to investigate the association between DII and mental disorders (depression, anxiety, and stress) using multilevel modeling to minimize the bias of the previous methods.MethodsThis cross-sectional analytical study was conducted using data from the initial phase of the Tehran University of Medical Sciences Employees’ Cohort Study (TEC). Nutritional information was obtained through a dish-based semi-quantitative food frequency questionnaire (DFQ), while psychological data were collected using the depression, anxiety and stress scale (DASS-42). The acquired data were analyzed using multilevel modeling in three levels (foods, nutrients, and DII, respectively) through GLIMMIX in the SAS software.ResultsA total of 3,501 individuals participated in this study. The results of the multilevel model demonstrated a significant statistical association between DII and mental disorders after adjusting for baseline characteristics, nutrients and foods. For each unit increase in DII, the mean scores for stress, anxiety, and depression increased by 3.55, 4.26, and 3.02, respectively (p < 0.001).ConclusionBased on the multilevel model’s findings, it is recommended to minimize the use of pro-inflammatory nutrients and foods to increase the mental health. Multilevel data analysis has also been recommended in nutritional studies involving nested data to obtain more accurate and plausible estimates. |
| first_indexed | 2024-03-08T14:35:50Z |
| format | Article |
| id | doaj.art-0468ba06a9e14a4e9503cd264209a9ac |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-03-08T14:35:50Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-0468ba06a9e14a4e9503cd264209a9ac2024-01-12T04:39:17ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2024-01-011110.3389/fnut.2024.12887931288793Association between dietary inflammatory index and mental disorders using multilevel modeling with GLIMMIXReza Beiranvand0Mohammad Ali Mansournia1Farhad Vahid2Ali-Akbar Nejatisafa3Saharnaz Nedjat4Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, IranDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, IranNutrition and Health Group, School of Heath, Arak University of Medical Science, Arak, IranPsychosomatic Research Center, Department of Psychiatry, Tehran University of Medical Sciences, Iranian Association of Psychosomatic Medicine, Tehran, IranSchool of Public Health, Tehran University of Medical Sciences, Tehran, IranIntroductionThe Dietary Inflammatory Index (DII) is a composite nutritional index that has gained significant attention in the past decade due to its association with physical and mental well-being. To accurately assess the precise effects of DII on health outcomes, the effects of nutrients and foods need to be adjusted. This study aimed to investigate the association between DII and mental disorders (depression, anxiety, and stress) using multilevel modeling to minimize the bias of the previous methods.MethodsThis cross-sectional analytical study was conducted using data from the initial phase of the Tehran University of Medical Sciences Employees’ Cohort Study (TEC). Nutritional information was obtained through a dish-based semi-quantitative food frequency questionnaire (DFQ), while psychological data were collected using the depression, anxiety and stress scale (DASS-42). The acquired data were analyzed using multilevel modeling in three levels (foods, nutrients, and DII, respectively) through GLIMMIX in the SAS software.ResultsA total of 3,501 individuals participated in this study. The results of the multilevel model demonstrated a significant statistical association between DII and mental disorders after adjusting for baseline characteristics, nutrients and foods. For each unit increase in DII, the mean scores for stress, anxiety, and depression increased by 3.55, 4.26, and 3.02, respectively (p < 0.001).ConclusionBased on the multilevel model’s findings, it is recommended to minimize the use of pro-inflammatory nutrients and foods to increase the mental health. Multilevel data analysis has also been recommended in nutritional studies involving nested data to obtain more accurate and plausible estimates.https://www.frontiersin.org/articles/10.3389/fnut.2024.1288793/fulldietary inflammatory indexmental disordersmultilevel modelGLIMMIXDiI |
| spellingShingle | Reza Beiranvand Mohammad Ali Mansournia Farhad Vahid Ali-Akbar Nejatisafa Saharnaz Nedjat Association between dietary inflammatory index and mental disorders using multilevel modeling with GLIMMIX Frontiers in Nutrition dietary inflammatory index mental disorders multilevel model GLIMMIX DiI |
| title | Association between dietary inflammatory index and mental disorders using multilevel modeling with GLIMMIX |
| title_full | Association between dietary inflammatory index and mental disorders using multilevel modeling with GLIMMIX |
| title_fullStr | Association between dietary inflammatory index and mental disorders using multilevel modeling with GLIMMIX |
| title_full_unstemmed | Association between dietary inflammatory index and mental disorders using multilevel modeling with GLIMMIX |
| title_short | Association between dietary inflammatory index and mental disorders using multilevel modeling with GLIMMIX |
| title_sort | association between dietary inflammatory index and mental disorders using multilevel modeling with glimmix |
| topic | dietary inflammatory index mental disorders multilevel model GLIMMIX DiI |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2024.1288793/full |
| work_keys_str_mv | AT rezabeiranvand associationbetweendietaryinflammatoryindexandmentaldisordersusingmultilevelmodelingwithglimmix AT mohammadalimansournia associationbetweendietaryinflammatoryindexandmentaldisordersusingmultilevelmodelingwithglimmix AT farhadvahid associationbetweendietaryinflammatoryindexandmentaldisordersusingmultilevelmodelingwithglimmix AT aliakbarnejatisafa associationbetweendietaryinflammatoryindexandmentaldisordersusingmultilevelmodelingwithglimmix AT saharnaznedjat associationbetweendietaryinflammatoryindexandmentaldisordersusingmultilevelmodelingwithglimmix |