Application of GLAD-PCR Assay for Study on DNA Methylation in Regulatory Regions of Some Tumor-Suppressor Genes in Lung Cancer

Application of GLAD-PCR Assay for Study on DNA Methylation in Regulatory Regions of Some Tumor-Suppressor Genes in Lung Cancer

Hypermethylation of the gene regulatory regions are common for many cancer diseases. In this work we applied GLAD-PCR assay for identificating of the aberrantly methylated RCGY sites in the regulatory regions of some downregulated genes in tissue samples of lung cancer (LC). This list includes EFEMP...

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Bibliographic Details
Main Authors: N.A. Smetannikova, A.A. Evdokimov, N.A. Netesova, M.A. Abdurashitov, A.G. Akishev, E.V. Dubinin, P.I. Pozdnyakov, I.V. Vihlyanov, M.K. Nikitin, E.B. Topolnitsky, A.B. Karpov, S.A. Kolomiets, S.Kh. Degtyarev
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2019-09-01
Series:Chinese Journal of Lung Cancer
Subjects:
Lung neoplasms
DNA methylation
GLAD-PCR
Diagnostics
Epigenetics
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2019.09.01

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