Giant cell tumor of a rib following denosumab treatment
Giant cell tumor (GCT) of the bone is an aggressive lytic lesion, commonly treated with surgery. Denosumab is a relatively recently introduced osteoclast activation inhibitor used for neoadjuvant therapy of GCT. Here we report the case of a GCT of a rib undergoing extensive osteosclerosis on compute...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-10-01
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| Series: | Radiology Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043318301201 |
| _version_ | 1818197631869911040 |
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| author | Alexandre Semionov John Kosiuk |
| author_facet | Alexandre Semionov John Kosiuk |
| author_sort | Alexandre Semionov |
| collection | DOAJ |
| description | Giant cell tumor (GCT) of the bone is an aggressive lytic lesion, commonly treated with surgery. Denosumab is a relatively recently introduced osteoclast activation inhibitor used for neoadjuvant therapy of GCT. Here we report the case of a GCT of a rib undergoing extensive osteosclerosis on computed tomography imaging following treatment with denosumab. Keywords: Giant cell tumor, Denosumab, Osteosclerosis |
| first_indexed | 2024-12-12T01:53:03Z |
| format | Article |
| id | doaj.art-046ce7ec7d394695bd328c901aad0610 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-12T01:53:03Z |
| publishDate | 2018-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-046ce7ec7d394695bd328c901aad06102022-12-22T00:42:26ZengElsevierRadiology Case Reports1930-04332018-10-0113510181020Giant cell tumor of a rib following denosumab treatmentAlexandre Semionov0John Kosiuk1Corresponding author.; McGill University Health Centre, Department of Diagnostic Radiology, Montreal General Hospital, 1650 Cedar Avenue, Montreal, QC H3G 1A4, CanadaMcGill University Health Centre, Department of Diagnostic Radiology, Montreal General Hospital, 1650 Cedar Avenue, Montreal, QC H3G 1A4, CanadaGiant cell tumor (GCT) of the bone is an aggressive lytic lesion, commonly treated with surgery. Denosumab is a relatively recently introduced osteoclast activation inhibitor used for neoadjuvant therapy of GCT. Here we report the case of a GCT of a rib undergoing extensive osteosclerosis on computed tomography imaging following treatment with denosumab. Keywords: Giant cell tumor, Denosumab, Osteosclerosishttp://www.sciencedirect.com/science/article/pii/S1930043318301201 |
| spellingShingle | Alexandre Semionov John Kosiuk Giant cell tumor of a rib following denosumab treatment Radiology Case Reports |
| title | Giant cell tumor of a rib following denosumab treatment |
| title_full | Giant cell tumor of a rib following denosumab treatment |
| title_fullStr | Giant cell tumor of a rib following denosumab treatment |
| title_full_unstemmed | Giant cell tumor of a rib following denosumab treatment |
| title_short | Giant cell tumor of a rib following denosumab treatment |
| title_sort | giant cell tumor of a rib following denosumab treatment |
| url | http://www.sciencedirect.com/science/article/pii/S1930043318301201 |
| work_keys_str_mv | AT alexandresemionov giantcelltumorofaribfollowingdenosumabtreatment AT johnkosiuk giantcelltumorofaribfollowingdenosumabtreatment |