Age at First Gestation in Beef Heifers Affects Fetal and Postnatal Growth, Glucose Metabolism and IGF1 Concentration
This study aimed to determine the effects of age at first gestation on offspring growth performance, glucose metabolism, and IGF1 concentration. Heifers impregnated by AI from a single bull at 15 months of age (15 M, n = 20), or 27 months of age (27 M, <i>n</i> = 20), and multiparous cow...
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MDPI AG
2021-11-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/11/12/3393 |
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| author | Sebastian López Valiente Alejandro M. Rodríguez Nathan M. Long Graciela Quintans Florencia E. Miccoli Isabel M. Lacau-Mengido Sebastian Maresca |
| author_facet | Sebastian López Valiente Alejandro M. Rodríguez Nathan M. Long Graciela Quintans Florencia E. Miccoli Isabel M. Lacau-Mengido Sebastian Maresca |
| author_sort | Sebastian López Valiente |
| collection | DOAJ |
| description | This study aimed to determine the effects of age at first gestation on offspring growth performance, glucose metabolism, and IGF1 concentration. Heifers impregnated by AI from a single bull at 15 months of age (15 M, n = 20), or 27 months of age (27 M, <i>n</i> = 20), and multiparous cows (adult, <i>n</i> = 20) were used. Dams from all groups were managed in a single group during gestation and lactation. Gestational length was longer in the 15 M and 27 M than in adult dams (<i>p</i> = 0.009). Bodyweight at birth, at weaning and ADG during lactation were higher in calves from adult dams than in those from 27 M dams, and higher in calves from the latter than in 15 M calves (<i>p</i> < 0.001). Calves from 15 M dams had an increased head circumference/BW ratio compared to calves from 27 M dams, while calves from this latter group had an increased ratio compared to calves from adults (<i>p</i> = 0.005). Body mass index was greater in calves from adults than in those from 15 M and 27 M dams (<i>p</i> = 0.002). Milk production from 15 M and 27 M dams was similar but lower than that from adults (<i>p</i> = 0.03). Calves born from adult dams had greater blood glucose concentrations than those from 15 M and 27 M dams (<i>p</i> < 0.05). Serum IGF1 concentrations were higher in calves from adults than in calves from 15 M and 27 M dams (<i>p</i> = 0.01). This study showed that age at first gestation affects offspring postnatal growth performance, glucose metabolism and IGF1 concentration. |
| first_indexed | 2024-03-10T04:40:09Z |
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| id | doaj.art-046d1a315f774f2bb21475a212a79eef |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T04:40:09Z |
| publishDate | 2021-11-01 |
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| record_format | Article |
| series | Animals |
| spelling | doaj.art-046d1a315f774f2bb21475a212a79eef2023-11-23T03:26:15ZengMDPI AGAnimals2076-26152021-11-011112339310.3390/ani11123393Age at First Gestation in Beef Heifers Affects Fetal and Postnatal Growth, Glucose Metabolism and IGF1 ConcentrationSebastian López Valiente0Alejandro M. Rodríguez1Nathan M. Long2Graciela Quintans3Florencia E. Miccoli4Isabel M. Lacau-Mengido5Sebastian Maresca6Estación Experimental Agropecuaria Cuenca del Salado, Instituto Nacional de Tecnología Agropecuaria, Rauch BA 7203, ArgentinaEstación Experimental Agropecuaria Cuenca del Salado, Instituto Nacional de Tecnología Agropecuaria, Rauch BA 7203, ArgentinaDepartment of Animal and Veterinary Sciences, Clemson University, Clemson, SC 29634, USAInstituto Nacional de Investigación Agropecuaria, Treinta y Tres 33000, UruguayFacultad de Ciencias Agrarias, Universidad Nacional de Lomas de Zamora, Lomas de Zamora BA 1836, ArgentinaLaboratorio de Regulación Hipofisaria, Instituto de Biología y Medicina Experimental (CONICET), Buenos Aires 1428, ArgentinaEstación Experimental Agropecuaria Cuenca del Salado, Instituto Nacional de Tecnología Agropecuaria, Rauch BA 7203, ArgentinaThis study aimed to determine the effects of age at first gestation on offspring growth performance, glucose metabolism, and IGF1 concentration. Heifers impregnated by AI from a single bull at 15 months of age (15 M, n = 20), or 27 months of age (27 M, <i>n</i> = 20), and multiparous cows (adult, <i>n</i> = 20) were used. Dams from all groups were managed in a single group during gestation and lactation. Gestational length was longer in the 15 M and 27 M than in adult dams (<i>p</i> = 0.009). Bodyweight at birth, at weaning and ADG during lactation were higher in calves from adult dams than in those from 27 M dams, and higher in calves from the latter than in 15 M calves (<i>p</i> < 0.001). Calves from 15 M dams had an increased head circumference/BW ratio compared to calves from 27 M dams, while calves from this latter group had an increased ratio compared to calves from adults (<i>p</i> = 0.005). Body mass index was greater in calves from adults than in those from 15 M and 27 M dams (<i>p</i> = 0.002). Milk production from 15 M and 27 M dams was similar but lower than that from adults (<i>p</i> = 0.03). Calves born from adult dams had greater blood glucose concentrations than those from 15 M and 27 M dams (<i>p</i> < 0.05). Serum IGF1 concentrations were higher in calves from adults than in calves from 15 M and 27 M dams (<i>p</i> = 0.01). This study showed that age at first gestation affects offspring postnatal growth performance, glucose metabolism and IGF1 concentration.https://www.mdpi.com/2076-2615/11/12/3393dam agefetal programmingbovinegrowthoffspring |
| spellingShingle | Sebastian López Valiente Alejandro M. Rodríguez Nathan M. Long Graciela Quintans Florencia E. Miccoli Isabel M. Lacau-Mengido Sebastian Maresca Age at First Gestation in Beef Heifers Affects Fetal and Postnatal Growth, Glucose Metabolism and IGF1 Concentration Animals dam age fetal programming bovine growth offspring |
| title | Age at First Gestation in Beef Heifers Affects Fetal and Postnatal Growth, Glucose Metabolism and IGF1 Concentration |
| title_full | Age at First Gestation in Beef Heifers Affects Fetal and Postnatal Growth, Glucose Metabolism and IGF1 Concentration |
| title_fullStr | Age at First Gestation in Beef Heifers Affects Fetal and Postnatal Growth, Glucose Metabolism and IGF1 Concentration |
| title_full_unstemmed | Age at First Gestation in Beef Heifers Affects Fetal and Postnatal Growth, Glucose Metabolism and IGF1 Concentration |
| title_short | Age at First Gestation in Beef Heifers Affects Fetal and Postnatal Growth, Glucose Metabolism and IGF1 Concentration |
| title_sort | age at first gestation in beef heifers affects fetal and postnatal growth glucose metabolism and igf1 concentration |
| topic | dam age fetal programming bovine growth offspring |
| url | https://www.mdpi.com/2076-2615/11/12/3393 |
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