The metabolic activity of the enteric microflora and the pattern of sensitization in different types of feeding in healthy infants
Objective: to investigate the metabolic activity of the enteric microflora and the rate of milk protein sensitization during different types of feeding in healthy infants of Moscow. A total of 200 apparently healthy children were followed up. According to feeding patterns, there were 100 formula-fed...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | Russian |
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Ltd. “The National Academy of Pediatric Science and Innovation”
2016-03-01
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| Series: | Rossijskij Vestnik Perinatologii i Pediatrii |
| Subjects: | |
| Online Access: | https://www.ped-perinatology.ru/jour/article/view/168 |
| _version_ | 1797875283956596736 |
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| author | S. V. Bogdanova T. B. Sentsova S. N. Denisova L. I. Ilienko V. A. Revyakina O. V. Tarasova O. O. Chernyak |
| author_facet | S. V. Bogdanova T. B. Sentsova S. N. Denisova L. I. Ilienko V. A. Revyakina O. V. Tarasova O. O. Chernyak |
| author_sort | S. V. Bogdanova |
| collection | DOAJ |
| description | Objective: to investigate the metabolic activity of the enteric microflora and the rate of milk protein sensitization during different types of feeding in healthy infants of Moscow. A total of 200 apparently healthy children were followed up. According to feeding patterns, there were 100 formula-fed babies (a study group) and 100 breast-fed ones (a comparison group). Subgroup 1 of the study group included 51 infants receiving formulas based on New Zealand goat's milk with prebiotics; Subgroup 2 consisted of 49 infants having formulas based on cow's milk-serum proteins with prebiotics. The metabolic activity of the enteric microflora was investigated by gas liquid chromatography; the concentrations of allergen-specific IgE and IgG antibodies against cow's and goat's milk proteins in coprofllrates were determined by noncompetitive enzyme immunoassay using special test systems (Allergopharma, Germany) before and during the ingestion of the formulas with prebiotics. The use of the formulas containing prebiotics led to increases in acetic acid and butyric acid concentrations and anaerobic index in both subgroups. However, their highest values in the coproflltrates were observed in Subgroup 1 and breast-fed infants. Analysis of allergen-specific IgE and IgC antibodies before formula indigestion showed that the level of latent sensitization to goat's milk protein was substantially lower than that to cow's milk protein (+ Class 1 and + Class 2, respectively). Subgroup 1 showed a more pronounced tendency to decrease the rate of latent sensitization to these types of protein. Thus, the most pronounced positive tendency in the examined indicators was observed in babies receiving breast milk or formulas based on New Zealand goat's milk with prebiotics. |
| first_indexed | 2024-04-10T01:45:11Z |
| format | Article |
| id | doaj.art-046f862411174fc98aab0410187c6628 |
| institution | Directory Open Access Journal |
| issn | 1027-4065 2500-2228 |
| language | Russian |
| last_indexed | 2024-04-10T01:45:11Z |
| publishDate | 2016-03-01 |
| publisher | Ltd. “The National Academy of Pediatric Science and Innovation” |
| record_format | Article |
| series | Rossijskij Vestnik Perinatologii i Pediatrii |
| spelling | doaj.art-046f862411174fc98aab0410187c66282023-03-13T09:12:41ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282016-03-01605135142161The metabolic activity of the enteric microflora and the pattern of sensitization in different types of feeding in healthy infantsS. V. Bogdanova0T. B. Sentsova1S. N. Denisova2L. I. Ilienko3V. A. Revyakina4O. V. Tarasova5O. O. Chernyak6Городская поликлиника №219, Москва; ФГБУ«НИИ питания» РАМН, МоскваГородская поликлиника №219, Москва; ФГБУ«НИИ питания» РАМН, МоскваГородская поликлиника №219, Москва; ФГБУ«НИИ питания» РАМН, МоскваРоссийский национальный исследовательский медицинский университет им. Н.И. Пирогова, МоскваГородская поликлиника №219, Москва; ФГБУ«НИИ питания» РАМН, МоскваРоссийский национальный исследовательский медицинский университет им. Н.И. Пирогова, МоскваN.I. Pirogov Russian National Research Medical University, Moscow; City Polyclinic Two Hundred and Nineteen, MoscowObjective: to investigate the metabolic activity of the enteric microflora and the rate of milk protein sensitization during different types of feeding in healthy infants of Moscow. A total of 200 apparently healthy children were followed up. According to feeding patterns, there were 100 formula-fed babies (a study group) and 100 breast-fed ones (a comparison group). Subgroup 1 of the study group included 51 infants receiving formulas based on New Zealand goat's milk with prebiotics; Subgroup 2 consisted of 49 infants having formulas based on cow's milk-serum proteins with prebiotics. The metabolic activity of the enteric microflora was investigated by gas liquid chromatography; the concentrations of allergen-specific IgE and IgG antibodies against cow's and goat's milk proteins in coprofllrates were determined by noncompetitive enzyme immunoassay using special test systems (Allergopharma, Germany) before and during the ingestion of the formulas with prebiotics. The use of the formulas containing prebiotics led to increases in acetic acid and butyric acid concentrations and anaerobic index in both subgroups. However, their highest values in the coproflltrates were observed in Subgroup 1 and breast-fed infants. Analysis of allergen-specific IgE and IgC antibodies before formula indigestion showed that the level of latent sensitization to goat's milk protein was substantially lower than that to cow's milk protein (+ Class 1 and + Class 2, respectively). Subgroup 1 showed a more pronounced tendency to decrease the rate of latent sensitization to these types of protein. Thus, the most pronounced positive tendency in the examined indicators was observed in babies receiving breast milk or formulas based on New Zealand goat's milk with prebiotics.https://www.ped-perinatology.ru/jour/article/view/168здоровые детилетучие жирные кислотыпищевая сенсибилизацияпитание. |
| spellingShingle | S. V. Bogdanova T. B. Sentsova S. N. Denisova L. I. Ilienko V. A. Revyakina O. V. Tarasova O. O. Chernyak The metabolic activity of the enteric microflora and the pattern of sensitization in different types of feeding in healthy infants Rossijskij Vestnik Perinatologii i Pediatrii здоровые дети летучие жирные кислоты пищевая сенсибилизация питание. |
| title | The metabolic activity of the enteric microflora and the pattern of sensitization in different types of feeding in healthy infants |
| title_full | The metabolic activity of the enteric microflora and the pattern of sensitization in different types of feeding in healthy infants |
| title_fullStr | The metabolic activity of the enteric microflora and the pattern of sensitization in different types of feeding in healthy infants |
| title_full_unstemmed | The metabolic activity of the enteric microflora and the pattern of sensitization in different types of feeding in healthy infants |
| title_short | The metabolic activity of the enteric microflora and the pattern of sensitization in different types of feeding in healthy infants |
| title_sort | metabolic activity of the enteric microflora and the pattern of sensitization in different types of feeding in healthy infants |
| topic | здоровые дети летучие жирные кислоты пищевая сенсибилизация питание. |
| url | https://www.ped-perinatology.ru/jour/article/view/168 |
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