The Density and Length of Filopodia Associate with the Activity of Hyaluronan Synthesis in Tumor Cells
Filopodia are multifunctional finger-like plasma membrane protrusions with bundles of actin filaments that exist in virtually all cell types. It has been known for some time that hyaluronan synthesis activity induces filopodial growth. However, because of technical challenges in the studies of these...
Main Authors: | Heikki Kyykallio, Sanna Oikari, María Bueno Álvez, Carlos José Gallardo Dodd, Janne Capra, Kirsi Rilla |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-07-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/12/7/1908 |
Similar Items
-
Hyaluronan synthase 1 (HAS1): A mysterious enzyme with unexpected functions
by: Hanna eSiiskonen, et al.
Published: (2015-02-01) -
CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells
by: Kai Härkönen, et al.
Published: (2019-03-01) -
MCF10CA Breast Cancer Cells Utilize Hyaluronan-Coated EV-Rich Trails for Coordinated Migration
by: Niina Aaltonen, et al.
Published: (2022-04-01) -
Elevated expression of hyaluronan synthase 2 associates with decreased survival in diffusely infiltrating astrocytomas
by: Mari Valkonen, et al.
Published: (2018-06-01) -
Dissecting the Dual Nature of Hyaluronan in the Tumor Microenvironment
by: Muhan Liu, et al.
Published: (2019-05-01)