Status and Advances of RGD Molecular Imaging in Lung Cancer
Lung cancer has been one of the most common and the highest mortality rates malignant tumors at home and abroad. Sustained angiogenesis was not only the characteristic of malignant tumors, but also the foundation of tumor proliferation, invasion, recurrence and metastasis, it was also one of the hot...
| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
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Chinese Anti-Cancer Association; Chinese Antituberculosis Association
2014-12-01
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| Series: | Chinese Journal of Lung Cancer |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.3779/j.issn.1009-3419.2014.12.06 |
| _version_ | 1828185341416177664 |
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| author | Ning YUE Shuanghu YUAN Guoren YANG |
| author_facet | Ning YUE Shuanghu YUAN Guoren YANG |
| author_sort | Ning YUE |
| collection | DOAJ |
| description | Lung cancer has been one of the most common and the highest mortality rates malignant tumors at home and abroad. Sustained angiogenesis was not only the characteristic of malignant tumors, but also the foundation of tumor proliferation, invasion, recurrence and metastasis, it was also one of the hot spots of treatments in lung cancer biology currently. Integrins played an important part in tumor angiogenesis. Arg-Gly-Asp (RGD) peptides could combine with integrins specifically, and the application of radionuclide-labeled RGD molecular probes enabled imaging of tumor blood vessels to reflect its changes. The lung cancer imaging of RGD peptides at home and abroad in recent years was reviewed in this article. |
| first_indexed | 2024-04-12T07:02:08Z |
| format | Article |
| id | doaj.art-04721c9d843b4a4193b621bf151b5d61 |
| institution | Directory Open Access Journal |
| issn | 1009-3419 |
| language | zho |
| last_indexed | 2024-04-12T07:02:08Z |
| publishDate | 2014-12-01 |
| publisher | Chinese Anti-Cancer Association; Chinese Antituberculosis Association |
| record_format | Article |
| series | Chinese Journal of Lung Cancer |
| spelling | doaj.art-04721c9d843b4a4193b621bf151b5d612022-12-22T03:42:57ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34192014-12-01171285585910.3779/j.issn.1009-3419.2014.12.06Status and Advances of RGD Molecular Imaging in Lung CancerNing YUE0Shuanghu YUAN1Guoren YANG2Department of Nuclear Medicine, Shandong Cancer Hospital, Shandong Academy of Medical Sciences, Jinan 250117, ChinaDepartment of Nuclear Medicine, Shandong Cancer Hospital, Shandong Academy of Medical Sciences, Jinan 250117, ChinaDepartment of Nuclear Medicine, Shandong Cancer Hospital, Shandong Academy of Medical Sciences, Jinan 250117, ChinaLung cancer has been one of the most common and the highest mortality rates malignant tumors at home and abroad. Sustained angiogenesis was not only the characteristic of malignant tumors, but also the foundation of tumor proliferation, invasion, recurrence and metastasis, it was also one of the hot spots of treatments in lung cancer biology currently. Integrins played an important part in tumor angiogenesis. Arg-Gly-Asp (RGD) peptides could combine with integrins specifically, and the application of radionuclide-labeled RGD molecular probes enabled imaging of tumor blood vessels to reflect its changes. The lung cancer imaging of RGD peptides at home and abroad in recent years was reviewed in this article.http://dx.doi.org/10.3779/j.issn.1009-3419.2014.12.06RGDIntegrinLung neoplasmsMolecular imagingAngiogenesis |
| spellingShingle | Ning YUE Shuanghu YUAN Guoren YANG Status and Advances of RGD Molecular Imaging in Lung Cancer Chinese Journal of Lung Cancer RGD Integrin Lung neoplasms Molecular imaging Angiogenesis |
| title | Status and Advances of RGD Molecular Imaging in Lung Cancer |
| title_full | Status and Advances of RGD Molecular Imaging in Lung Cancer |
| title_fullStr | Status and Advances of RGD Molecular Imaging in Lung Cancer |
| title_full_unstemmed | Status and Advances of RGD Molecular Imaging in Lung Cancer |
| title_short | Status and Advances of RGD Molecular Imaging in Lung Cancer |
| title_sort | status and advances of rgd molecular imaging in lung cancer |
| topic | RGD Integrin Lung neoplasms Molecular imaging Angiogenesis |
| url | http://dx.doi.org/10.3779/j.issn.1009-3419.2014.12.06 |
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