Differential Spatial Gene and Protein Expression Associated with Recurrence Following Chemoradiation for Localized Anal Squamous Cell Cancer

Differential Spatial Gene and Protein Expression Associated with Recurrence Following Chemoradiation for Localized Anal Squamous Cell Cancer

The identification of transcriptomic and protein biomarkers prognosticating recurrence risk after chemoradiation of localized squamous cell carcinoma of the anus (SCCA) has been limited by a lack of available fresh tissue at initial presentation. We analyzed archival FFPE SCCA specimens from pretrea...

Full description

Bibliographic Details
Main Authors: Sharia Hernandez, Prajnan Das, Emma B. Holliday, Li Shen, Wei Lu, Benny Johnson, Craig A. Messick, Cullen M. Taniguchi, John Skibber, Ethan B. Ludmir, Y. Nancy You, Grace Li Smith, Brian Bednarski, Larisa Kostousov, Eugene J. Koay, Bruce D. Minsky, Matthew Tillman, Shaelynn Portier, Cathy Eng, Albert C. Koong, George J. Chang, Wai Chin Foo, Jing Wang, Luisa Solis Soto, Van K. Morris
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
squamous anal cell carcinoma
chemoradiation
recurrence
protein profiling
digital spatial profiling
Online Access:https://www.mdpi.com/2072-6694/15/6/1701

Similar Items

Similar Items