Small RNA Sequencing Reveals a Distinct MicroRNA Signature between Glucocorticoid Responder and Glucocorticoid Non-Responder Primary Human Trabecular Meshwork Cells after Dexamethasone Treatment

Small RNA Sequencing Reveals a Distinct MicroRNA Signature between Glucocorticoid Responder and Glucocorticoid Non-Responder Primary Human Trabecular Meshwork Cells after Dexamethasone Treatment

Glucocorticoids (GCs) are known to regulate several physiological processes and are the mainstay in the management of inflammatory eye diseases. The long-term use of GC causes raised intraocular pressure (IOP) or ocular hypertension (OHT) in about 30–50% of the susceptible individuals depending on t...

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Bibliographic Details
Main Authors: Kandasamy Kathirvel, Xiaochen Fan, Ravinarayanan Haribalaganesh, Devarajan Bharanidharan, Rajendrababu Sharmila, Ramasamy Krishnadas, Veerappan Muthukkaruppan, Colin E. Willoughby, Srinivasan Senthilkumari
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Genes
Subjects:
glucocorticoids
glaucoma
microRNAs
miRNA
trabecular meshwork
small RNA-Seq
Online Access:https://www.mdpi.com/2073-4425/14/11/2012

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