Hydroxyapatite-lignin composite as a metallic implant-bone tissue osseointegration improver: experimental study in dogs
The study aimed to evaluate biocompatibility, osteoconduction and osseointegration of a pasty composite of hydroxyapatite (20%) and lignin (80%) as a promoter of metal implant and bone tissue integration. An intramedullary Schanz pin was implanted in both tibias of fifteen bitches. In the left tibia...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Universidade Federal de Santa Maria
2015-01-01
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| Series: | Ciência Rural |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015005050110&lng=en&tlng=en |
| _version_ | 1811307608486707200 |
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| author | Fabrício Luciani Valente Letícia Corrêa Santos Rodrigo Viana Sepúlveda Gustavo Pereira Gonçalves Renato Barros Eleotério Emily Correna Carlo Reis Andréa Pacheco Batista Borges |
| author_facet | Fabrício Luciani Valente Letícia Corrêa Santos Rodrigo Viana Sepúlveda Gustavo Pereira Gonçalves Renato Barros Eleotério Emily Correna Carlo Reis Andréa Pacheco Batista Borges |
| author_sort | Fabrício Luciani Valente |
| collection | DOAJ |
| description | The study aimed to evaluate biocompatibility, osteoconduction and osseointegration of a pasty composite of hydroxyapatite (20%) and lignin (80%) as a promoter of metal implant and bone tissue integration. An intramedullary Schanz pin was implanted in both tibias of fifteen bitches. In the left tibia, the pin was coated with the biomaterial at the time of surgery. Marrow cavity was also filled with the biomaterial. Right limb did not receive the biomaterial, then constituting the control group. Tibias were harvested from five animals at 8, 60 and 150 days after surgery; three of them were analyzed by histological and biomechanical assessment and the two remaining tibias by X-ray diffraction. Results showed that the biomaterial is biocompatible, with osteoconductivity and osseointegration properties. Histological analysis and diffractograms showed the presence of hydroxyapatite in samples in all periods, although the presence of organic material of low crystallinity was variable. There was no statistical difference in the forces required for removal of the biocompatibility, osteoconductivity and osseointegration, it was not able to promote a better intramedullary pin anchorage. |
| first_indexed | 2024-04-13T09:07:50Z |
| format | Article |
| id | doaj.art-047a7579f14c4131871eeac5dd013ed8 |
| institution | Directory Open Access Journal |
| issn | 1678-4596 |
| language | English |
| last_indexed | 2024-04-13T09:07:50Z |
| publishDate | 2015-01-01 |
| publisher | Universidade Federal de Santa Maria |
| record_format | Article |
| series | Ciência Rural |
| spelling | doaj.art-047a7579f14c4131871eeac5dd013ed82022-12-22T02:52:57ZengUniversidade Federal de Santa MariaCiência Rural1678-45962015-01-0100010.1590/0103-8478cr20150110S0103-84782015005050110Hydroxyapatite-lignin composite as a metallic implant-bone tissue osseointegration improver: experimental study in dogsFabrício Luciani ValenteLetícia Corrêa SantosRodrigo Viana SepúlvedaGustavo Pereira GonçalvesRenato Barros EleotérioEmily Correna Carlo ReisAndréa Pacheco Batista BorgesThe study aimed to evaluate biocompatibility, osteoconduction and osseointegration of a pasty composite of hydroxyapatite (20%) and lignin (80%) as a promoter of metal implant and bone tissue integration. An intramedullary Schanz pin was implanted in both tibias of fifteen bitches. In the left tibia, the pin was coated with the biomaterial at the time of surgery. Marrow cavity was also filled with the biomaterial. Right limb did not receive the biomaterial, then constituting the control group. Tibias were harvested from five animals at 8, 60 and 150 days after surgery; three of them were analyzed by histological and biomechanical assessment and the two remaining tibias by X-ray diffraction. Results showed that the biomaterial is biocompatible, with osteoconductivity and osseointegration properties. Histological analysis and diffractograms showed the presence of hydroxyapatite in samples in all periods, although the presence of organic material of low crystallinity was variable. There was no statistical difference in the forces required for removal of the biocompatibility, osteoconductivity and osseointegration, it was not able to promote a better intramedullary pin anchorage.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015005050110&lng=en&tlng=enbiomaterialbiocompatibilidadeosseointegraçãoosteoconduçãoregeneração tecidual |
| spellingShingle | Fabrício Luciani Valente Letícia Corrêa Santos Rodrigo Viana Sepúlveda Gustavo Pereira Gonçalves Renato Barros Eleotério Emily Correna Carlo Reis Andréa Pacheco Batista Borges Hydroxyapatite-lignin composite as a metallic implant-bone tissue osseointegration improver: experimental study in dogs Ciência Rural biomaterial biocompatibilidade osseointegração osteocondução regeneração tecidual |
| title | Hydroxyapatite-lignin composite as a metallic implant-bone tissue osseointegration improver: experimental study in dogs |
| title_full | Hydroxyapatite-lignin composite as a metallic implant-bone tissue osseointegration improver: experimental study in dogs |
| title_fullStr | Hydroxyapatite-lignin composite as a metallic implant-bone tissue osseointegration improver: experimental study in dogs |
| title_full_unstemmed | Hydroxyapatite-lignin composite as a metallic implant-bone tissue osseointegration improver: experimental study in dogs |
| title_short | Hydroxyapatite-lignin composite as a metallic implant-bone tissue osseointegration improver: experimental study in dogs |
| title_sort | hydroxyapatite lignin composite as a metallic implant bone tissue osseointegration improver experimental study in dogs |
| topic | biomaterial biocompatibilidade osseointegração osteocondução regeneração tecidual |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015005050110&lng=en&tlng=en |
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