Stage Specific Expression Pattern of Alpha-Hemoglobin-Stabilizing-Protein (AHSP) Portrayed in Erythroblast Chronology

Stage Specific Expression Pattern of Alpha-Hemoglobin-Stabilizing-Protein (AHSP) Portrayed in Erythroblast Chronology

During erythropoiesis, the molecular chaperone alpha-hemoglobin-stabilizing protein (AHSP) sequesters free alpha-hemoglobin (<i>α</i>Hb) and prevents precipitation of excess <i>α</i>Hb. While AHSP is linked to hereditary anemia, the pattern of expression during specific eryth...

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Bibliographic Details
Main Authors: Julia Walczak, Maria D. Camargo Johnson, Kuzhali Muthumalaiappan
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Methods and Protocols
Subjects:
AHSP
alpha-hemoglobin-stabilizing-protein
erythropoiesis
enucleation
human bone marrow
biphasic erythroid culture
Online Access:https://www.mdpi.com/2409-9279/3/3/46

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