Frequencies of two CYP2C19 defective alleles (CYP2C19*2, and *3) among Iranian population in Mazandaran Province
Background: Cytochrome P450 2C19 (CYP2C19) is a polymorphically expressed enzyme that shows marked interindividual and interethnic variation. CYP2C19*2 and CYP2C19*3 are the most frequently identified defective alleles in Orientals and Caucasian poor metabolizers (PM). The aim of this study was to i...
Main Authors: | Naghi Shahabi-Majd, Mohammad bagher Hashemi-Sotehoh, Baharak Habashi, Mohammad reza Shiran |
---|---|
Format: | Article |
Language: | English |
Published: |
Mazandaran University of Medical Sciences and Health Services
2013-02-01
|
Series: | Research in Molecular Medicine |
Subjects: | |
Online Access: | http://rmm.mazums.ac.ir/browse.php?a_code=A-10-326-1&slc_lang=en&sid=1 |
Similar Items
-
Detection of CYP2C18 m1, and m2 Alleles within an Iranian Population (Mazandaran) Using Denaturing High-Performance Liquid Chromatography (DHPLC)
by: Adeleh Rafati, et al.
Published: (2015-04-01) -
Polymorphisms of CYP1A1 Gene Variants m1 and m2 and Their Association with the Incidence of Cancer in West of Mazandaran Province, Iran
by: Saba Sadat Hosseini, et al.
Published: (2018-10-01) -
Functional characterization of the defective CYP2C9 variant CYP2C9*18
by: Jian Liu, et al.
Published: (2021-02-01) -
Prevalence of CYP2C19*2 and CYP2C19*3 Allelic Variants and Clopidogrel Use in Patients with Cardiovascular Disease in Trinidad & Tobago
by: Daniele Jones, et al.
Published: (2024-01-01) -
Identification and drug metabolic characterization of four new CYP2C9 variants CYP2C9*72-*75 in the Chinese Han population
by: Fang-Ling Zhao, et al.
Published: (2022-12-01)