Current approaches to development of contrast agents for MRI diagnostics
Magnetic resonance imaging (MRI) is primarily used in medical imaging to visualize the structure and function of the body and essential tool for diagnostics of broad range of pathologies. But still in a growing number of cases there are indications to use contrast agent to delineate areas of interes...
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Format: | Article |
Language: | English |
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Siberian State Medical University (Tomsk)
2011-12-01
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Series: | Бюллетень сибирской медицины |
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Online Access: | https://bulletin.ssmu.ru/jour/article/view/1506 |
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author | K. N. Sorokina A. A. Tulupov T. G. Tolstikova V. Yu. Ussov |
author_facet | K. N. Sorokina A. A. Tulupov T. G. Tolstikova V. Yu. Ussov |
author_sort | K. N. Sorokina |
collection | DOAJ |
description | Magnetic resonance imaging (MRI) is primarily used in medical imaging to visualize the structure and function of the body and essential tool for diagnostics of broad range of pathologies. But still in a growing number of cases there are indications to use contrast agent to delineate areas of interest and for more precise diagnosis definition. In a review the properties and clinical applications of most popular paramagnetic contrast agents based on Gd(III), Fe(II) и Mn(II) are discussed. It is also focused on discussion of modern experimental targeted contrast agents (conjugates of antibodies, nanoparticles and dendrimers) and advances of their application for early diagnostics of most common pathologies: cardiovascular, cancer and Alzheimer diseases. |
first_indexed | 2024-04-10T01:09:20Z |
format | Article |
id | doaj.art-0485bf6e74394d48b19f03e08dce7369 |
institution | Directory Open Access Journal |
issn | 1682-0363 1819-3684 |
language | English |
last_indexed | 2024-04-10T01:09:20Z |
publishDate | 2011-12-01 |
publisher | Siberian State Medical University (Tomsk) |
record_format | Article |
series | Бюллетень сибирской медицины |
spelling | doaj.art-0485bf6e74394d48b19f03e08dce73692023-03-13T09:58:15ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842011-12-01106798510.20538/1682-0363-2011-6-79-851012Current approaches to development of contrast agents for MRI diagnosticsK. N. Sorokina0A. A. Tulupov1T. G. Tolstikova2V. Yu. Ussov3Институт катализа им. Г.К. Борескова СО РАНИнститут «Международный томографический центр» СО РАНИнститут органической химии им. Н.Н. Ворожцова СО РАНИнститут «Международный томографический центр» СО РАНMagnetic resonance imaging (MRI) is primarily used in medical imaging to visualize the structure and function of the body and essential tool for diagnostics of broad range of pathologies. But still in a growing number of cases there are indications to use contrast agent to delineate areas of interest and for more precise diagnosis definition. In a review the properties and clinical applications of most popular paramagnetic contrast agents based on Gd(III), Fe(II) и Mn(II) are discussed. It is also focused on discussion of modern experimental targeted contrast agents (conjugates of antibodies, nanoparticles and dendrimers) and advances of their application for early diagnostics of most common pathologies: cardiovascular, cancer and Alzheimer diseases.https://bulletin.ssmu.ru/jour/article/view/1506магнитно-резонансная томографияконтрастные агенты для мртэкспериментальные контрастные препараты |
spellingShingle | K. N. Sorokina A. A. Tulupov T. G. Tolstikova V. Yu. Ussov Current approaches to development of contrast agents for MRI diagnostics Бюллетень сибирской медицины магнитно-резонансная томография контрастные агенты для мрт экспериментальные контрастные препараты |
title | Current approaches to development of contrast agents for MRI diagnostics |
title_full | Current approaches to development of contrast agents for MRI diagnostics |
title_fullStr | Current approaches to development of contrast agents for MRI diagnostics |
title_full_unstemmed | Current approaches to development of contrast agents for MRI diagnostics |
title_short | Current approaches to development of contrast agents for MRI diagnostics |
title_sort | current approaches to development of contrast agents for mri diagnostics |
topic | магнитно-резонансная томография контрастные агенты для мрт экспериментальные контрастные препараты |
url | https://bulletin.ssmu.ru/jour/article/view/1506 |
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