Optimal neuromuscular blocking effects of remifentanil during tracheal intubation under general anesthesia
Objective This study was performed to determine the effect of the remifentanil dose on the onset time of rocuronium with electromyography. Methods This retrospective comparative study included 75 patients undergoing general anesthesia for elective surgery. Patients received lidocaine (40 mg) and pro...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2018-08-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/0300060518772227 |
| _version_ | 1818577691057586176 |
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| author | So Young Kwon Si Wook Chung Jin Deok Joo |
| author_facet | So Young Kwon Si Wook Chung Jin Deok Joo |
| author_sort | So Young Kwon |
| collection | DOAJ |
| description | Objective This study was performed to determine the effect of the remifentanil dose on the onset time of rocuronium with electromyography. Methods This retrospective comparative study included 75 patients undergoing general anesthesia for elective surgery. Patients received lidocaine (40 mg) and propofol (2 mg/kg) followed by rocuronium (0.6 mg/kg) with either saline infusion (Group S), remifentanil at 0.5 µg/kg/minute (Group R 0.5), or remifentanil at 1.0 µg/kg/minute (Group R 1.0). Neuromuscular block was monitored by train-of-four (TOF) electromyography, and the times taken to reach TOF 0 and TOF ratio (TOFR) 25% were recorded. Results The times taken to reach TOF 0 and TOFR 25% were significantly higher in Groups R 0.5 and R 1.0 than in Group S. The time taken to reach TOF 0 was 130.0 ± 6.4 s in Group S, 142.6 ± 6.0 s in Group R 0.5, and 183.0 ± 11.6 s in Group R 1.0. The time taken to reach TOFR 25% was also higher in Groups R 0.5 and R 1.0 than in Group S. Conclusions As the remifentanil dose increases, the intubation time required to reach TOF 0 also increases. Remifentanil has an effect on the onset of rocuronium. |
| first_indexed | 2024-12-16T06:33:56Z |
| format | Article |
| id | doaj.art-048708d058cf49398a70c288ee9359bc |
| institution | Directory Open Access Journal |
| issn | 0300-0605 1473-2300 |
| language | English |
| last_indexed | 2024-12-16T06:33:56Z |
| publishDate | 2018-08-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-048708d058cf49398a70c288ee9359bc2022-12-21T22:40:50ZengSAGE PublishingJournal of International Medical Research0300-06051473-23002018-08-014610.1177/0300060518772227Optimal neuromuscular blocking effects of remifentanil during tracheal intubation under general anesthesiaSo Young KwonSi Wook ChungJin Deok JooObjective This study was performed to determine the effect of the remifentanil dose on the onset time of rocuronium with electromyography. Methods This retrospective comparative study included 75 patients undergoing general anesthesia for elective surgery. Patients received lidocaine (40 mg) and propofol (2 mg/kg) followed by rocuronium (0.6 mg/kg) with either saline infusion (Group S), remifentanil at 0.5 µg/kg/minute (Group R 0.5), or remifentanil at 1.0 µg/kg/minute (Group R 1.0). Neuromuscular block was monitored by train-of-four (TOF) electromyography, and the times taken to reach TOF 0 and TOF ratio (TOFR) 25% were recorded. Results The times taken to reach TOF 0 and TOFR 25% were significantly higher in Groups R 0.5 and R 1.0 than in Group S. The time taken to reach TOF 0 was 130.0 ± 6.4 s in Group S, 142.6 ± 6.0 s in Group R 0.5, and 183.0 ± 11.6 s in Group R 1.0. The time taken to reach TOFR 25% was also higher in Groups R 0.5 and R 1.0 than in Group S. Conclusions As the remifentanil dose increases, the intubation time required to reach TOF 0 also increases. Remifentanil has an effect on the onset of rocuronium.https://doi.org/10.1177/0300060518772227 |
| spellingShingle | So Young Kwon Si Wook Chung Jin Deok Joo Optimal neuromuscular blocking effects of remifentanil during tracheal intubation under general anesthesia Journal of International Medical Research |
| title | Optimal neuromuscular blocking effects of remifentanil during tracheal intubation under general anesthesia |
| title_full | Optimal neuromuscular blocking effects of remifentanil during tracheal intubation under general anesthesia |
| title_fullStr | Optimal neuromuscular blocking effects of remifentanil during tracheal intubation under general anesthesia |
| title_full_unstemmed | Optimal neuromuscular blocking effects of remifentanil during tracheal intubation under general anesthesia |
| title_short | Optimal neuromuscular blocking effects of remifentanil during tracheal intubation under general anesthesia |
| title_sort | optimal neuromuscular blocking effects of remifentanil during tracheal intubation under general anesthesia |
| url | https://doi.org/10.1177/0300060518772227 |
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