Neuroprotection by inhibiting the c-Jun N-terminal kinase pathway after cerebral ischemia occurs independently of interleukin-6 and keratinocyte-derived chemokine (KC/CXCL1) secretion

Neuroprotection by inhibiting the c-Jun N-terminal kinase pathway after cerebral ischemia occurs independently of interleukin-6 and keratinocyte-derived chemokine (KC/CXCL1) secretion

<p>Abstract</p> <p>Background</p> <p>Cerebral ischemia is associated with the activation of glial cells, infiltration of leukocytes and an increase in inflammatory mediators in the ischemic brain and systemic circulation. How this inflammatory response influences lesion...

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Bibliographic Details
Main Authors: Benakis Corinne, Vaslin Anne, Pasquali Christian, Hirt Lorenz
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Journal of Neuroinflammation
Subjects:
c-Jun N-terminal kinase
Inflammation
Interleukin-6
Keratinocyte-derived chemokine
Middle cerebral artery occlusion
Neuroprotection
Online Access:http://www.jneuroinflammation.com/content/9/1/76

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