Combined spinal and epidural anesthesia with dexmedetomidine sedation during hip and knee arthroplasty
Background. Hip and knee arthroplasty (HKA) is a common surgical procedure. One of the common diseases that negatively affect the results of these operations is diabetes. The aim of the study: to determine the effectiveness and safety of combined multimodal low-opioid anesthesia with dexmedetomidine...
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| Format: | Article |
| Language: | English |
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Zaslavsky O.Yu.
2022-11-01
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| Series: | Медицина неотложных состояний |
| Subjects: | |
| Online Access: | https://emergency.zaslavsky.com.ua/index.php/journal/article/view/1528 |
| _version_ | 1827992670632411136 |
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| author | O.A. Halushko L.M. Zenkina |
| author_facet | O.A. Halushko L.M. Zenkina |
| author_sort | O.A. Halushko |
| collection | DOAJ |
| description | Background. Hip and knee arthroplasty (HKA) is a common surgical procedure. One of the common diseases that negatively affect the results of these operations is diabetes. The aim of the study: to determine the effectiveness and safety of combined multimodal low-opioid anesthesia with dexmedetomidine sedation in patients undergoing HKA in concomitant diabetes mellitus. Materials and methods. In total, the study included 45 patients who underwent HKA. They were divided into 3 groups depending on the scheme of anesthesia. In group 1 (n = 15), multicomponent low-flow anesthesia with artificial lung ventilation was performed; in group 2 (n = 15), spinal anesthesia was used; in group 3 (n = 15), combined spinal and epidural anesthesia with dexmedetomidine sedation was performed. Results. The course of anesthesia in all groups was satisfactory, but patients in group 3 were less likely to experience hyperdynamic reactions (tachycardia and hypotension), postoperative nausea and vomiting. Only one person from group 3 required ondansetron for the treatment of postoperative nausea and vomiting against 3 and 2 patients from groups 1 and 2, respectively (p < 0.05). Conclusions. Any of the proposed techniques can be used for anesthesia in HKA, but the best results have been obtained in combined spinal and epidural anesthesia with dexmedetomidine sedation. |
| first_indexed | 2024-04-10T04:12:18Z |
| format | Article |
| id | doaj.art-048834d7e9b14cc082da1acfdabe4cf8 |
| institution | Directory Open Access Journal |
| issn | 2224-0586 2307-1230 |
| language | English |
| last_indexed | 2024-04-10T04:12:18Z |
| publishDate | 2022-11-01 |
| publisher | Zaslavsky O.Yu. |
| record_format | Article |
| series | Медицина неотложных состояний |
| spelling | doaj.art-048834d7e9b14cc082da1acfdabe4cf82023-03-12T15:45:44ZengZaslavsky O.Yu.Медицина неотложных состояний2224-05862307-12302022-11-01187293310.22141/2224-0586.18.7.2022.15281528Combined spinal and epidural anesthesia with dexmedetomidine sedation during hip and knee arthroplastyO.A. Halushko0https://orcid.org/0000-0001-7027-8110L.M. Zenkina1Shupyk National Healthcare University of Ukraine, Kyiv, UkraineCenter for Innovative Medical Technologies of the National Academy of Sciences of Ukraine, Kyiv, UkraineBackground. Hip and knee arthroplasty (HKA) is a common surgical procedure. One of the common diseases that negatively affect the results of these operations is diabetes. The aim of the study: to determine the effectiveness and safety of combined multimodal low-opioid anesthesia with dexmedetomidine sedation in patients undergoing HKA in concomitant diabetes mellitus. Materials and methods. In total, the study included 45 patients who underwent HKA. They were divided into 3 groups depending on the scheme of anesthesia. In group 1 (n = 15), multicomponent low-flow anesthesia with artificial lung ventilation was performed; in group 2 (n = 15), spinal anesthesia was used; in group 3 (n = 15), combined spinal and epidural anesthesia with dexmedetomidine sedation was performed. Results. The course of anesthesia in all groups was satisfactory, but patients in group 3 were less likely to experience hyperdynamic reactions (tachycardia and hypotension), postoperative nausea and vomiting. Only one person from group 3 required ondansetron for the treatment of postoperative nausea and vomiting against 3 and 2 patients from groups 1 and 2, respectively (p < 0.05). Conclusions. Any of the proposed techniques can be used for anesthesia in HKA, but the best results have been obtained in combined spinal and epidural anesthesia with dexmedetomidine sedation.https://emergency.zaslavsky.com.ua/index.php/journal/article/view/1528hip arthroplastyknee arthroplastydiabetes mellituscomplicationsdexmedetomidine |
| spellingShingle | O.A. Halushko L.M. Zenkina Combined spinal and epidural anesthesia with dexmedetomidine sedation during hip and knee arthroplasty Медицина неотложных состояний hip arthroplasty knee arthroplasty diabetes mellitus complications dexmedetomidine |
| title | Combined spinal and epidural anesthesia with dexmedetomidine sedation during hip and knee arthroplasty |
| title_full | Combined spinal and epidural anesthesia with dexmedetomidine sedation during hip and knee arthroplasty |
| title_fullStr | Combined spinal and epidural anesthesia with dexmedetomidine sedation during hip and knee arthroplasty |
| title_full_unstemmed | Combined spinal and epidural anesthesia with dexmedetomidine sedation during hip and knee arthroplasty |
| title_short | Combined spinal and epidural anesthesia with dexmedetomidine sedation during hip and knee arthroplasty |
| title_sort | combined spinal and epidural anesthesia with dexmedetomidine sedation during hip and knee arthroplasty |
| topic | hip arthroplasty knee arthroplasty diabetes mellitus complications dexmedetomidine |
| url | https://emergency.zaslavsky.com.ua/index.php/journal/article/view/1528 |
| work_keys_str_mv | AT oahalushko combinedspinalandepiduralanesthesiawithdexmedetomidinesedationduringhipandkneearthroplasty AT lmzenkina combinedspinalandepiduralanesthesiawithdexmedetomidinesedationduringhipandkneearthroplasty |