RBBP7, regulated by SP1, enhances the Warburg effect to facilitate the proliferation of hepatocellular carcinoma cells via PI3K/AKT signaling

RBBP7, regulated by SP1, enhances the Warburg effect to facilitate the proliferation of hepatocellular carcinoma cells via PI3K/AKT signaling

Abstract Background Hepatocellular carcinoma (HCC) is characterized by aggressive progression and elevated mortality rates. This study aimed to investigate the regulatory effects of RBBP7 on HCC pathogenesis and the underlying mechanisms. Methods The expression and clinical feature of RBBP7 were eva...

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Bibliographic Details
Main Authors: Yuan Fang, WeiQiang Tang, Siming Qu, ZhiTao Li, XiaoLi Zhang, YingLei Miao, Zhong Zeng, HanFei Huang
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Translational Medicine
Subjects:
RBBP7
Glycolysis
SP1
Hepatocellular carcinoma
Proliferation
Online Access:https://doi.org/10.1186/s12967-024-04964-8

Internet

https://doi.org/10.1186/s12967-024-04964-8

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