Eldecalcitol prevents muscle loss and osteoporosis in disuse muscle atrophy via NF-κB signaling in mice

Eldecalcitol prevents muscle loss and osteoporosis in disuse muscle atrophy via NF-κB signaling in mice

Abstract We investigated the effect of eldecalcitol on disuse muscle atrophy. C57BL/6J male mice aged 6 weeks were randomly assigned to control, tail suspension (TS), and TS-eldecalcitol–treated groups and were injected intraperitoneally twice a week with either vehicle (control and TS) or eldecalci...

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Bibliographic Details
Main Authors: Haichao Zhang, Yanping Du, Wenjing Tang, Minmin Chen, Weijia Yu, Zheng Ke, Shuangshuang Dong, Qun Cheng
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Skeletal Muscle
Subjects:
Eldecalcitol
Tail suspension
Grip strength
Vitamin D receptor
NF-κB signaling
Online Access:https://doi.org/10.1186/s13395-023-00332-0

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