Multimodal Imaging of Reticular Pseudodrusen in Turkish Patients
Objectives:To investigate the presence and prevalence of reticular pseudodrusen (RPD) in patients with age-related macular degeneration using multiple imaging modalities and to compare the sensitivity and specificity of these modalities in the detection of RPD.Materials and Methods:Images from a tot...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2023-10-01
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| Series: | Türk Oftalmoloji Dergisi |
| Subjects: | |
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http://www.oftalmoloji.org/archives/archive-detail/article-preview/multimodal-maging-of-reticular-pseudodrusen-in-tur/62814
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| _version_ | 1797646370990981120 |
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| author | Serap Bilge Çeper Filiz Afrashi Cumali Değirmenci Jale Menteş Serhad Nalçacı Cezmi Akkın |
| author_facet | Serap Bilge Çeper Filiz Afrashi Cumali Değirmenci Jale Menteş Serhad Nalçacı Cezmi Akkın |
| author_sort | Serap Bilge Çeper |
| collection | DOAJ |
| description | Objectives:To investigate the presence and prevalence of reticular pseudodrusen (RPD) in patients with age-related macular degeneration using multiple imaging modalities and to compare the sensitivity and specificity of these modalities in the detection of RPD.Materials and Methods:Images from a total of 198 consecutive patients were analyzed prospectively. Color fundus photography, red-free imaging, spectral domain optical coherence tomography (SD-OCT), infrared and blue reflectance (BR) imaging, fundus autofluorescence (FAF), enhanced-depth imaging OCT (EDI-OCT), fundus fluorescein angiography (FFA) and indocyanine green angiography were performed. RPD was diagnosed in the presence of relevant findings in at least two of the imaging methods used.Results:RPD were detected in 149 eyes (37.6%). In the detection of RPD, color fundus photography, red-free photography, SD-OCT, infrared, FAF, BR, and FFA imaging had sensitivity values of 50%, 57.7%, 91.6%, 95%, 74.6%, 65.7%, and 28.2% and specificity values of 99.6%, 100%, 98.4%, 94.6%, 100%, 99.6%, and 69.8%, respectively.Conclusion:Infrared imaging had the highest sensitivity. SD-OCT combined with infrared imaging was the most sensitive imaging technique for detecting RPD. The high specificity of FAF, red-free, and BR imaging may be useful to confirm a diagnosis of RPD. |
| first_indexed | 2024-03-11T15:00:24Z |
| format | Article |
| id | doaj.art-0493efb2e1e444d187f759c2f2e31243 |
| institution | Directory Open Access Journal |
| issn | 1300-0659 2147-2661 |
| language | English |
| last_indexed | 2024-03-11T15:00:24Z |
| publishDate | 2023-10-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Oftalmoloji Dergisi |
| spelling | doaj.art-0493efb2e1e444d187f759c2f2e312432023-10-30T07:36:11ZengGalenos YayineviTürk Oftalmoloji Dergisi1300-06592147-26612023-10-0153527528010.4274/tjo.galenos.2023.8561613049054Multimodal Imaging of Reticular Pseudodrusen in Turkish PatientsSerap Bilge Çeper0Filiz Afrashi1Cumali Değirmenci2Jale Menteş3Serhad Nalçacı4Cezmi Akkın5 Malatya Eğitim ve Araştırma Hastanesi, Göz Hastalıkları Kliniği, Malatya, Türkiye Ege Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, İzmir, Türkiye Ege Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, İzmir, Türkiye Ege Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, İzmir, Türkiye Ege Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, İzmir, Türkiye Ege Üniversitesi Tıp Fakültesi, Göz Hastalıkları Anabilim Dalı, İzmir, Türkiye Objectives:To investigate the presence and prevalence of reticular pseudodrusen (RPD) in patients with age-related macular degeneration using multiple imaging modalities and to compare the sensitivity and specificity of these modalities in the detection of RPD.Materials and Methods:Images from a total of 198 consecutive patients were analyzed prospectively. Color fundus photography, red-free imaging, spectral domain optical coherence tomography (SD-OCT), infrared and blue reflectance (BR) imaging, fundus autofluorescence (FAF), enhanced-depth imaging OCT (EDI-OCT), fundus fluorescein angiography (FFA) and indocyanine green angiography were performed. RPD was diagnosed in the presence of relevant findings in at least two of the imaging methods used.Results:RPD were detected in 149 eyes (37.6%). In the detection of RPD, color fundus photography, red-free photography, SD-OCT, infrared, FAF, BR, and FFA imaging had sensitivity values of 50%, 57.7%, 91.6%, 95%, 74.6%, 65.7%, and 28.2% and specificity values of 99.6%, 100%, 98.4%, 94.6%, 100%, 99.6%, and 69.8%, respectively.Conclusion:Infrared imaging had the highest sensitivity. SD-OCT combined with infrared imaging was the most sensitive imaging technique for detecting RPD. The high specificity of FAF, red-free, and BR imaging may be useful to confirm a diagnosis of RPD. http://www.oftalmoloji.org/archives/archive-detail/article-preview/multimodal-maging-of-reticular-pseudodrusen-in-tur/62814 age-related macular degenerationimaging methodsreticular pseudodrusenturkish patients |
| spellingShingle | Serap Bilge Çeper Filiz Afrashi Cumali Değirmenci Jale Menteş Serhad Nalçacı Cezmi Akkın Multimodal Imaging of Reticular Pseudodrusen in Turkish Patients Türk Oftalmoloji Dergisi age-related macular degeneration imaging methods reticular pseudodrusen turkish patients |
| title | Multimodal Imaging of Reticular Pseudodrusen in Turkish Patients |
| title_full | Multimodal Imaging of Reticular Pseudodrusen in Turkish Patients |
| title_fullStr | Multimodal Imaging of Reticular Pseudodrusen in Turkish Patients |
| title_full_unstemmed | Multimodal Imaging of Reticular Pseudodrusen in Turkish Patients |
| title_short | Multimodal Imaging of Reticular Pseudodrusen in Turkish Patients |
| title_sort | multimodal imaging of reticular pseudodrusen in turkish patients |
| topic | age-related macular degeneration imaging methods reticular pseudodrusen turkish patients |
| url |
http://www.oftalmoloji.org/archives/archive-detail/article-preview/multimodal-maging-of-reticular-pseudodrusen-in-tur/62814
|
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