Bloodstream and endovascular infections due to <it>Abiotrophia defectiva </it>and <it>Granulicatella </it>species
<p>Abstract</p> <p>Background</p> <p><it>Abiotrophia </it>and <it>Granulicatella </it>species, previously referred to as nutritionally variant streptococci (NVS), are significant causative agents of endocarditis and bacteraemia. In this study, we...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2006-01-01
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| Series: | BMC Infectious Diseases |
| Online Access: | http://www.biomedcentral.com/1471-2334/6/9 |
| _version_ | 1818541753286787072 |
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| author | Bille Jacques Wenger Aline Jaton Katia Greub Gilbert Entenza José M Senn Laurence Calandra Thierry Prod'hom Guy |
| author_facet | Bille Jacques Wenger Aline Jaton Katia Greub Gilbert Entenza José M Senn Laurence Calandra Thierry Prod'hom Guy |
| author_sort | Bille Jacques |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p><it>Abiotrophia </it>and <it>Granulicatella </it>species, previously referred to as nutritionally variant streptococci (NVS), are significant causative agents of endocarditis and bacteraemia. In this study, we reviewed the clinical manifestations of infections due to <it>A. defectiva </it>and <it>Granulicatella </it>species that occurred at our institution between 1998 and 2004.</p> <p>Methods</p> <p>The analysis included all strains of NVS that were isolated from blood cultures or vascular graft specimens. All strains were identified by 16S rRNA sequence analysis. Patients' medical charts were reviewed for each case of infection.</p> <p>Results</p> <p>Eleven strains of NVS were isolated during the 6-year period. Identification of the strains by 16S rRNA showed 2 genogroups: <it>Abiotrophia defectiva </it>(3) and <it>Granulicatella adiacens </it>(6) or <it>"para-adiacens" </it>(2). The three <it>A. defectiva </it>strains were isolated from immunocompetent patients with endovascular infections, whereas 7 of 8 <it>Granulicatella </it>spp. strains were isolated from immunosuppressed patients, mainly febrile neutropenic patients. We report the first case of <it>"G. para-adiacens" </it>bacteraemia in the setting of febrile neutropenia.</p> <p>Conclusion</p> <p>We propose that <it>Granulicatella </it>spp. be considered as a possible agent of bacteraemia in neutropenic patients.</p> |
| first_indexed | 2024-12-11T22:13:19Z |
| format | Article |
| id | doaj.art-04993f59af8b472fbe455be133db79fd |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-11T22:13:19Z |
| publishDate | 2006-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-04993f59af8b472fbe455be133db79fd2022-12-22T00:48:42ZengBMCBMC Infectious Diseases1471-23342006-01-0161910.1186/1471-2334-6-9Bloodstream and endovascular infections due to <it>Abiotrophia defectiva </it>and <it>Granulicatella </it>speciesBille JacquesWenger AlineJaton KatiaGreub GilbertEntenza José MSenn LaurenceCalandra ThierryProd'hom Guy<p>Abstract</p> <p>Background</p> <p><it>Abiotrophia </it>and <it>Granulicatella </it>species, previously referred to as nutritionally variant streptococci (NVS), are significant causative agents of endocarditis and bacteraemia. In this study, we reviewed the clinical manifestations of infections due to <it>A. defectiva </it>and <it>Granulicatella </it>species that occurred at our institution between 1998 and 2004.</p> <p>Methods</p> <p>The analysis included all strains of NVS that were isolated from blood cultures or vascular graft specimens. All strains were identified by 16S rRNA sequence analysis. Patients' medical charts were reviewed for each case of infection.</p> <p>Results</p> <p>Eleven strains of NVS were isolated during the 6-year period. Identification of the strains by 16S rRNA showed 2 genogroups: <it>Abiotrophia defectiva </it>(3) and <it>Granulicatella adiacens </it>(6) or <it>"para-adiacens" </it>(2). The three <it>A. defectiva </it>strains were isolated from immunocompetent patients with endovascular infections, whereas 7 of 8 <it>Granulicatella </it>spp. strains were isolated from immunosuppressed patients, mainly febrile neutropenic patients. We report the first case of <it>"G. para-adiacens" </it>bacteraemia in the setting of febrile neutropenia.</p> <p>Conclusion</p> <p>We propose that <it>Granulicatella </it>spp. be considered as a possible agent of bacteraemia in neutropenic patients.</p>http://www.biomedcentral.com/1471-2334/6/9 |
| spellingShingle | Bille Jacques Wenger Aline Jaton Katia Greub Gilbert Entenza José M Senn Laurence Calandra Thierry Prod'hom Guy Bloodstream and endovascular infections due to <it>Abiotrophia defectiva </it>and <it>Granulicatella </it>species BMC Infectious Diseases |
| title | Bloodstream and endovascular infections due to <it>Abiotrophia defectiva </it>and <it>Granulicatella </it>species |
| title_full | Bloodstream and endovascular infections due to <it>Abiotrophia defectiva </it>and <it>Granulicatella </it>species |
| title_fullStr | Bloodstream and endovascular infections due to <it>Abiotrophia defectiva </it>and <it>Granulicatella </it>species |
| title_full_unstemmed | Bloodstream and endovascular infections due to <it>Abiotrophia defectiva </it>and <it>Granulicatella </it>species |
| title_short | Bloodstream and endovascular infections due to <it>Abiotrophia defectiva </it>and <it>Granulicatella </it>species |
| title_sort | bloodstream and endovascular infections due to it abiotrophia defectiva it and it granulicatella it species |
| url | http://www.biomedcentral.com/1471-2334/6/9 |
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