Type 2 Diabetes and Atrial Fibrillation: Evaluating Causal and Pleiotropic Pathways Using Mendelian Randomization

Type 2 Diabetes and Atrial Fibrillation: Evaluating Causal and Pleiotropic Pathways Using Mendelian Randomization

Background Observational associations between type 2 diabetes (T2D) and atrial fibrillation (AF) have been established, but causality remains undetermined. We performed Mendelian randomization (MR) to study causal effects of genetically predicted T2D on AF risk, independent of cardiometabolic risk f...

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Bibliographic Details
Main Authors: Rohin K. Reddy, Maddalena Ardissino, Fu Siong Ng
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
atrial fibrillation
diabetes, type 2
genes
Mendelian randomization
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.030298

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