CC16 Regulates Inflammation, ROS Generation and Apoptosis in Bronchial Epithelial Cells during <i>Klebsiella pneumoniae</i> Infection

CC16 Regulates Inflammation, ROS Generation and Apoptosis in Bronchial Epithelial Cells during <i>Klebsiella pneumoniae</i> Infection

Gram-negative (G-) bacteria are the leading cause of hospital-acquired pneumonia in the United States. The devastating damage caused by G- bacteria results from the imbalance of bactericidal effects and overwhelming inflammation. Despite decades of research, the underlying mechanisms by which runawa...

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Bibliographic Details
Main Authors: Sultan Almuntashiri, Yohan Han, Yin Zhu, Saugata Dutta, Sara Niazi, Xiaoyun Wang, Budder Siddiqui, Duo Zhang
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
SCGB1A1
bacterial pneumonia
lung injury
cell death
innate immunity
NF-κB pathway
Online Access:https://www.mdpi.com/1422-0067/22/21/11459

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