BjussuLAAO-II induces cytotoxicity and alters DNA methylation of cell-cycle genes in monocultured/co-cultured HepG2 cells

BjussuLAAO-II induces cytotoxicity and alters DNA methylation of cell-cycle genes in monocultured/co-cultured HepG2 cells

Abstract Background: The use of animal venoms and their toxins as material sources for biotechnological applications has received much attention from the pharmaceutical industry. L-amino acid oxidases from snake venoms (SV-LAAOs) have demonstrated innumerous biological effects and pharmacological p...

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Bibliographic Details
Main Authors: Ana Rita Thomazela Machado, Alexandre Ferro Aissa, Diego Luis Ribeiro, Rui Seabra Ferreira Jr., Suely Vilela Sampaio, Lusânia Maria Greggi Antunes
Format: Article
Language:English
Published: SciELO 2019-03-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
snake venom
epigenetics
GADD45A
CCND1
CDKN1A
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100305&lng=en&tlng=en

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