Decreased Pyruvate but Not Fatty Acid Driven Mitochondrial Respiration in Skeletal Muscle of Growth Restricted Fetal Sheep

Decreased Pyruvate but Not Fatty Acid Driven Mitochondrial Respiration in Skeletal Muscle of Growth Restricted Fetal Sheep

Fetuses with intrauterine growth restriction (FGR) have impaired oxidative and energy metabolism, with persistent consequences on their postnatal development. In this study, we test the hypothesis that FGR skeletal muscle has lower mitochondrial respiration rate and alters the transcriptomic profile...

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Bibliographic Details
Main Authors:	Weicheng Zhao, Amy C. Kelly, Rosa I. Luna-Ramirez, Christopher A. Bidwell, Miranda J. Anderson, Sean W. Limesand
Format:	Article
Language:	English
Published:	MDPI AG 2023-10-01
Series:	International Journal of Molecular Sciences
Subjects:	intrauterine growth restriction mitochondria skeletal muscle fetus developmental programming
Online Access:	https://www.mdpi.com/1422-0067/24/21/15760

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