Genetics and pathophysiology of mitral valve prolapse

Genetics and pathophysiology of mitral valve prolapse

Mitral valve prolapse (MVP) is a common condition affecting 2–3% of the general population, and the most complex form of valve pathology, with a complication rate up to 10–15% per year in advanced stages. Complications include mitral regurgitation which can lead to heart failure and atrial fibrillat...

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Bibliographic Details
Main Authors: Constance Delwarde, Romain Capoulade, Jean Mérot, Solena Le Scouarnec, Nabila Bouatia-Naji, Mengyao Yu, Olivier Huttin, Christine Selton-Suty, Jean-Marc Sellal, Nicolas Piriou, Jean-Jacques Schott, Christian Dina, Thierry Le Tourneau
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
mitral valve prolapse
myxomatous disease
genetic
pathophysiology
animal models
Filamin A
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1077788/full

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