Radical hydrodifluoromethylation of unsaturated C−C bonds via an electroreductively triggered two-pronged approach
The installation of difluoromethylene groups into bio-relevant molecules allows access to important scaffolds, but existing methods to do so often rely on oxidative chemical species that can hamper reactivity. Here, radical hydrodifluoromethylation with a wide range of unsaturated C–C bonds is achie...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-08-01
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| Series: | Communications Chemistry |
| Online Access: | https://doi.org/10.1038/s42004-022-00697-1 |