Incidental benefits after fecal microbiota transplant for ulcerative colitis
Gut dysbiosis can result in several diseases, including infections (Clostridium difficile infection and infectious gastroenteritis), autoimmune diseases (inflammatory bowel disease, diabetes, and allergic disorders), behavioral disorders and other conditions like metabolic syndrome and functional ga...
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| Format: | Article |
| Language: | English |
| Published: |
Korean Association for the Study of Intestinal Diseases
2020-07-01
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| Series: | Intestinal Research |
| Subjects: | |
| Online Access: | http://www.irjournal.org/upload/pdf/ir-2019-00108.pdf |
| _version_ | 1818190408939732992 |
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| author | Ramit Mahajan Vandana Midha Arshdeep Singh Varun Mehta Yogesh Gupta Kirandeep Kaur Ritu Sudhakar Anmol Singh Pannu Dharmatma Singh Ajit Sood |
| author_facet | Ramit Mahajan Vandana Midha Arshdeep Singh Varun Mehta Yogesh Gupta Kirandeep Kaur Ritu Sudhakar Anmol Singh Pannu Dharmatma Singh Ajit Sood |
| author_sort | Ramit Mahajan |
| collection | DOAJ |
| description | Gut dysbiosis can result in several diseases, including infections (Clostridium difficile infection and infectious gastroenteritis), autoimmune diseases (inflammatory bowel disease, diabetes, and allergic disorders), behavioral disorders and other conditions like metabolic syndrome and functional gastrointestinal disorders. Amongst various therapies targeting gut microbiome, fecal microbiota transplantation (FMT) is becoming a focus in the public media and peer reviewed literature. We have been using FMT for induction of remission in patients with moderate to severe active ulcerative colitis (UC) and also for subsequent maintenance of remission. Four cases reported incidental benefits while being treated with FMT for UC. These included weight loss (n=1), improvement in hair loss (n=1), amelioration of axial arthritis (n=1) and improvement in allergic rhinitis (n=1), thereby suggesting potential clinical applications of FMT in treating extraintestinal diseases associated with gut dysbiosis. |
| first_indexed | 2024-12-11T23:58:15Z |
| format | Article |
| id | doaj.art-04a5fb3e404d4f628183e2a275743080 |
| institution | Directory Open Access Journal |
| issn | 1598-9100 2288-1956 |
| language | English |
| last_indexed | 2024-12-11T23:58:15Z |
| publishDate | 2020-07-01 |
| publisher | Korean Association for the Study of Intestinal Diseases |
| record_format | Article |
| series | Intestinal Research |
| spelling | doaj.art-04a5fb3e404d4f628183e2a2757430802022-12-22T00:45:18ZengKorean Association for the Study of Intestinal DiseasesIntestinal Research1598-91002288-19562020-07-0118333734010.5217/ir.2019.00108832Incidental benefits after fecal microbiota transplant for ulcerative colitisRamit Mahajan0Vandana Midha1Arshdeep Singh2Varun Mehta3Yogesh Gupta4Kirandeep Kaur5Ritu Sudhakar6Anmol Singh Pannu7Dharmatma Singh8Ajit Sood9 Department of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, India Department of Internal Medicine, Dayanand Medical College and Hospital, Ludhiana, India Department of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, India Department of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, India Department of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, India Department of Pharmacology, Dayanand Medical College and Hospital, Ludhiana, India Department of Dietetics, Dayanand Medical College and Hospital, Ludhiana, India Department of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, India Department of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, India Department of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, IndiaGut dysbiosis can result in several diseases, including infections (Clostridium difficile infection and infectious gastroenteritis), autoimmune diseases (inflammatory bowel disease, diabetes, and allergic disorders), behavioral disorders and other conditions like metabolic syndrome and functional gastrointestinal disorders. Amongst various therapies targeting gut microbiome, fecal microbiota transplantation (FMT) is becoming a focus in the public media and peer reviewed literature. We have been using FMT for induction of remission in patients with moderate to severe active ulcerative colitis (UC) and also for subsequent maintenance of remission. Four cases reported incidental benefits while being treated with FMT for UC. These included weight loss (n=1), improvement in hair loss (n=1), amelioration of axial arthritis (n=1) and improvement in allergic rhinitis (n=1), thereby suggesting potential clinical applications of FMT in treating extraintestinal diseases associated with gut dysbiosis.http://www.irjournal.org/upload/pdf/ir-2019-00108.pdffecal microbiota transplantationcolitis, ulcerativeincidental findings |
| spellingShingle | Ramit Mahajan Vandana Midha Arshdeep Singh Varun Mehta Yogesh Gupta Kirandeep Kaur Ritu Sudhakar Anmol Singh Pannu Dharmatma Singh Ajit Sood Incidental benefits after fecal microbiota transplant for ulcerative colitis Intestinal Research fecal microbiota transplantation colitis, ulcerative incidental findings |
| title | Incidental benefits after fecal microbiota transplant for ulcerative colitis |
| title_full | Incidental benefits after fecal microbiota transplant for ulcerative colitis |
| title_fullStr | Incidental benefits after fecal microbiota transplant for ulcerative colitis |
| title_full_unstemmed | Incidental benefits after fecal microbiota transplant for ulcerative colitis |
| title_short | Incidental benefits after fecal microbiota transplant for ulcerative colitis |
| title_sort | incidental benefits after fecal microbiota transplant for ulcerative colitis |
| topic | fecal microbiota transplantation colitis, ulcerative incidental findings |
| url | http://www.irjournal.org/upload/pdf/ir-2019-00108.pdf |
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