Nasopharyngeal carcinoma with pericardial metastasis

Nasopharyngeal carcinoma (NPC) is prevalent in Taiwan and is characterized by a high frequency of nodal metastasis. The most common organs with distal metastases are the bones, lungs, and liver, with extremely rare cases to the pericardium. Herein, we report a rare case with NPC who presented with d...

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Main Authors: Shang-Wen Chen, Chao-Hsun Chen, Chao-Jung Tsao, Wen-Tsung Huang, Shih-Sung Chuang
Format: Article
Language:English
Published: Wiley 2011-07-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X11000362
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author Shang-Wen Chen
Chao-Hsun Chen
Chao-Jung Tsao
Wen-Tsung Huang
Shih-Sung Chuang
author_facet Shang-Wen Chen
Chao-Hsun Chen
Chao-Jung Tsao
Wen-Tsung Huang
Shih-Sung Chuang
author_sort Shang-Wen Chen
collection DOAJ
description Nasopharyngeal carcinoma (NPC) is prevalent in Taiwan and is characterized by a high frequency of nodal metastasis. The most common organs with distal metastases are the bones, lungs, and liver, with extremely rare cases to the pericardium. Herein, we report a rare case with NPC who presented with dyspnea and orthopnea. Serial studies, including pericardial biopsy, revealed NPC with pericardial metastasis and pericardial effusion. The tumor cells of both the original and metastatic tumors were positive for Epstein–Barr virus by in situ hybridization. This is the first histologically confirmed case of NPC with pericardial metastasis.
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spelling doaj.art-04a6f3d3b655419b892055ec8566d8722022-12-21T19:38:23ZengWileyKaohsiung Journal of Medical Sciences1607-551X2011-07-0127728929110.1016/j.kjms.2010.08.005Nasopharyngeal carcinoma with pericardial metastasisShang-Wen Chen0Chao-Hsun Chen1Chao-Jung Tsao2Wen-Tsung Huang3Shih-Sung Chuang4Division of Hemato-Oncology, Department of Internal Medicine, Chi-Mei Medical Center, Liouying, Tainan, TaiwanDivision of Hemato-Oncology, Department of Internal Medicine, Chi-Mei Medical Center, Liouying, Tainan, TaiwanDivision of Hemato-Oncology, Department of Internal Medicine, Chi-Mei Medical Center, Liouying, Tainan, TaiwanDivision of Hemato-Oncology, Department of Internal Medicine, Chi-Mei Medical Center, Liouying, Tainan, TaiwanDepartment of Pathology, Chi-Mei Medical Center, Tainan, TaiwanNasopharyngeal carcinoma (NPC) is prevalent in Taiwan and is characterized by a high frequency of nodal metastasis. The most common organs with distal metastases are the bones, lungs, and liver, with extremely rare cases to the pericardium. Herein, we report a rare case with NPC who presented with dyspnea and orthopnea. Serial studies, including pericardial biopsy, revealed NPC with pericardial metastasis and pericardial effusion. The tumor cells of both the original and metastatic tumors were positive for Epstein–Barr virus by in situ hybridization. This is the first histologically confirmed case of NPC with pericardial metastasis.http://www.sciencedirect.com/science/article/pii/S1607551X11000362Epstein–Barr virusNasopharyngeal carcinomaPericardium
spellingShingle Shang-Wen Chen
Chao-Hsun Chen
Chao-Jung Tsao
Wen-Tsung Huang
Shih-Sung Chuang
Nasopharyngeal carcinoma with pericardial metastasis
Kaohsiung Journal of Medical Sciences
Epstein–Barr virus
Nasopharyngeal carcinoma
Pericardium
title Nasopharyngeal carcinoma with pericardial metastasis
title_full Nasopharyngeal carcinoma with pericardial metastasis
title_fullStr Nasopharyngeal carcinoma with pericardial metastasis
title_full_unstemmed Nasopharyngeal carcinoma with pericardial metastasis
title_short Nasopharyngeal carcinoma with pericardial metastasis
title_sort nasopharyngeal carcinoma with pericardial metastasis
topic Epstein–Barr virus
Nasopharyngeal carcinoma
Pericardium
url http://www.sciencedirect.com/science/article/pii/S1607551X11000362
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AT wentsunghuang nasopharyngealcarcinomawithpericardialmetastasis
AT shihsungchuang nasopharyngealcarcinomawithpericardialmetastasis