Nasopharyngeal carcinoma with pericardial metastasis
Nasopharyngeal carcinoma (NPC) is prevalent in Taiwan and is characterized by a high frequency of nodal metastasis. The most common organs with distal metastases are the bones, lungs, and liver, with extremely rare cases to the pericardium. Herein, we report a rare case with NPC who presented with d...
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Format: | Article |
Language: | English |
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Wiley
2011-07-01
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Series: | Kaohsiung Journal of Medical Sciences |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1607551X11000362 |
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author | Shang-Wen Chen Chao-Hsun Chen Chao-Jung Tsao Wen-Tsung Huang Shih-Sung Chuang |
author_facet | Shang-Wen Chen Chao-Hsun Chen Chao-Jung Tsao Wen-Tsung Huang Shih-Sung Chuang |
author_sort | Shang-Wen Chen |
collection | DOAJ |
description | Nasopharyngeal carcinoma (NPC) is prevalent in Taiwan and is characterized by a high frequency of nodal metastasis. The most common organs with distal metastases are the bones, lungs, and liver, with extremely rare cases to the pericardium. Herein, we report a rare case with NPC who presented with dyspnea and orthopnea. Serial studies, including pericardial biopsy, revealed NPC with pericardial metastasis and pericardial effusion. The tumor cells of both the original and metastatic tumors were positive for Epstein–Barr virus by in situ hybridization. This is the first histologically confirmed case of NPC with pericardial metastasis. |
first_indexed | 2024-12-20T13:59:59Z |
format | Article |
id | doaj.art-04a6f3d3b655419b892055ec8566d872 |
institution | Directory Open Access Journal |
issn | 1607-551X |
language | English |
last_indexed | 2024-12-20T13:59:59Z |
publishDate | 2011-07-01 |
publisher | Wiley |
record_format | Article |
series | Kaohsiung Journal of Medical Sciences |
spelling | doaj.art-04a6f3d3b655419b892055ec8566d8722022-12-21T19:38:23ZengWileyKaohsiung Journal of Medical Sciences1607-551X2011-07-0127728929110.1016/j.kjms.2010.08.005Nasopharyngeal carcinoma with pericardial metastasisShang-Wen Chen0Chao-Hsun Chen1Chao-Jung Tsao2Wen-Tsung Huang3Shih-Sung Chuang4Division of Hemato-Oncology, Department of Internal Medicine, Chi-Mei Medical Center, Liouying, Tainan, TaiwanDivision of Hemato-Oncology, Department of Internal Medicine, Chi-Mei Medical Center, Liouying, Tainan, TaiwanDivision of Hemato-Oncology, Department of Internal Medicine, Chi-Mei Medical Center, Liouying, Tainan, TaiwanDivision of Hemato-Oncology, Department of Internal Medicine, Chi-Mei Medical Center, Liouying, Tainan, TaiwanDepartment of Pathology, Chi-Mei Medical Center, Tainan, TaiwanNasopharyngeal carcinoma (NPC) is prevalent in Taiwan and is characterized by a high frequency of nodal metastasis. The most common organs with distal metastases are the bones, lungs, and liver, with extremely rare cases to the pericardium. Herein, we report a rare case with NPC who presented with dyspnea and orthopnea. Serial studies, including pericardial biopsy, revealed NPC with pericardial metastasis and pericardial effusion. The tumor cells of both the original and metastatic tumors were positive for Epstein–Barr virus by in situ hybridization. This is the first histologically confirmed case of NPC with pericardial metastasis.http://www.sciencedirect.com/science/article/pii/S1607551X11000362Epstein–Barr virusNasopharyngeal carcinomaPericardium |
spellingShingle | Shang-Wen Chen Chao-Hsun Chen Chao-Jung Tsao Wen-Tsung Huang Shih-Sung Chuang Nasopharyngeal carcinoma with pericardial metastasis Kaohsiung Journal of Medical Sciences Epstein–Barr virus Nasopharyngeal carcinoma Pericardium |
title | Nasopharyngeal carcinoma with pericardial metastasis |
title_full | Nasopharyngeal carcinoma with pericardial metastasis |
title_fullStr | Nasopharyngeal carcinoma with pericardial metastasis |
title_full_unstemmed | Nasopharyngeal carcinoma with pericardial metastasis |
title_short | Nasopharyngeal carcinoma with pericardial metastasis |
title_sort | nasopharyngeal carcinoma with pericardial metastasis |
topic | Epstein–Barr virus Nasopharyngeal carcinoma Pericardium |
url | http://www.sciencedirect.com/science/article/pii/S1607551X11000362 |
work_keys_str_mv | AT shangwenchen nasopharyngealcarcinomawithpericardialmetastasis AT chaohsunchen nasopharyngealcarcinomawithpericardialmetastasis AT chaojungtsao nasopharyngealcarcinomawithpericardialmetastasis AT wentsunghuang nasopharyngealcarcinomawithpericardialmetastasis AT shihsungchuang nasopharyngealcarcinomawithpericardialmetastasis |