Current Concepts in the Management of Primary Lymphedema
Primary lymphedema is a heterogeneous group of conditions encompassing all lymphatic anomalies that result in lymphatic swelling. Primary lymphedema can be difficult to diagnose, and diagnosis is often delayed. As opposed to secondary lymphedema, primary lymphedema has an unpredictable disease cours...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/5/894 |
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| author | Jenna-Lynn B. Senger Rohini L. Kadle Roman J. Skoracki |
| author_facet | Jenna-Lynn B. Senger Rohini L. Kadle Roman J. Skoracki |
| author_sort | Jenna-Lynn B. Senger |
| collection | DOAJ |
| description | Primary lymphedema is a heterogeneous group of conditions encompassing all lymphatic anomalies that result in lymphatic swelling. Primary lymphedema can be difficult to diagnose, and diagnosis is often delayed. As opposed to secondary lymphedema, primary lymphedema has an unpredictable disease course, often progressing more slowly. Primary lymphedema can be associated with various genetic syndromes or can be idiopathic. Diagnosis is often clinical, although imaging can be a helpful adjunct. The literature on treating primary lymphedema is limited, and treatment algorithms are largely based on practice patterns for secondary lymphedema. The mainstay of treatment focuses on complete decongestive therapy, including manual lymphatic drainage and compression therapy. For those who fail conservative treatment, surgical treatment can be an option. Microsurgical techniques have shown promise in primary lymphedema, with both lymphovenous bypass and vascularized lymph node transfers demonstrating improved clinical outcomes in a few studies. |
| first_indexed | 2024-03-11T03:30:55Z |
| format | Article |
| id | doaj.art-04a7c7ee487044349426d0293893daec |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-11T03:30:55Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-04a7c7ee487044349426d0293893daec2023-11-18T02:21:50ZengMDPI AGMedicina1010-660X1648-91442023-05-0159589410.3390/medicina59050894Current Concepts in the Management of Primary LymphedemaJenna-Lynn B. Senger0Rohini L. Kadle1Roman J. Skoracki2Wexner Medical Center, Department of Plastic Surgery, Ohio State University, Columbus, OH 43210, USAWexner Medical Center, Department of Plastic Surgery, Ohio State University, Columbus, OH 43210, USAWexner Medical Center, Department of Plastic Surgery, Ohio State University, Columbus, OH 43210, USAPrimary lymphedema is a heterogeneous group of conditions encompassing all lymphatic anomalies that result in lymphatic swelling. Primary lymphedema can be difficult to diagnose, and diagnosis is often delayed. As opposed to secondary lymphedema, primary lymphedema has an unpredictable disease course, often progressing more slowly. Primary lymphedema can be associated with various genetic syndromes or can be idiopathic. Diagnosis is often clinical, although imaging can be a helpful adjunct. The literature on treating primary lymphedema is limited, and treatment algorithms are largely based on practice patterns for secondary lymphedema. The mainstay of treatment focuses on complete decongestive therapy, including manual lymphatic drainage and compression therapy. For those who fail conservative treatment, surgical treatment can be an option. Microsurgical techniques have shown promise in primary lymphedema, with both lymphovenous bypass and vascularized lymph node transfers demonstrating improved clinical outcomes in a few studies.https://www.mdpi.com/1648-9144/59/5/894primary lymphedemacongenital lymphedemalymphovenous bypasslymphovenous anastomosisvascularized lymph node transfer |
| spellingShingle | Jenna-Lynn B. Senger Rohini L. Kadle Roman J. Skoracki Current Concepts in the Management of Primary Lymphedema Medicina primary lymphedema congenital lymphedema lymphovenous bypass lymphovenous anastomosis vascularized lymph node transfer |
| title | Current Concepts in the Management of Primary Lymphedema |
| title_full | Current Concepts in the Management of Primary Lymphedema |
| title_fullStr | Current Concepts in the Management of Primary Lymphedema |
| title_full_unstemmed | Current Concepts in the Management of Primary Lymphedema |
| title_short | Current Concepts in the Management of Primary Lymphedema |
| title_sort | current concepts in the management of primary lymphedema |
| topic | primary lymphedema congenital lymphedema lymphovenous bypass lymphovenous anastomosis vascularized lymph node transfer |
| url | https://www.mdpi.com/1648-9144/59/5/894 |
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