Detection of Nuclear Protein Profile Changes by Human Metapneumovirus M2-2 Protein Using Quantitative Differential Proteomics

Detection of Nuclear Protein Profile Changes by Human Metapneumovirus M2-2 Protein Using Quantitative Differential Proteomics

Human metapneumovirus (hMPV) is a leading cause of lower respiratory infection in pediatric populations globally. This study examined proteomic profile changes in A549 cells infected with hMPV and two attenuated mutants with deleted PDZ domain-binding motif(s) in the M2-2 protein. These motifs are i...

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Bibliographic Details
Main Authors: Yuping Ren, Eunjin Choi, Ke Zhang, Yu Chen, Sha Ye, Xiaoling Deng, Kangling Zhang, Xiaoyong Bao
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Vaccines
Subjects:
hMPV
M2-2 motif
proteomics
Online Access:https://www.mdpi.com/2076-393X/5/4/45

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