Tuberculin skin test and interferon-gamma release assay values are associated with antimicrobial peptides expression in  polymorphonuclear cells during latent tuberculous infection

Tuberculin skin test and interferon-gamma release assay values are associated with antimicrobial peptides expression in  polymorphonuclear cells during latent tuberculous infection

It has been reported that patients with progressive tuberculosis (TB) express abundant amounts of the antimicrobial peptides (AMPs) cathelicidin (LL-37) and human neutrophil peptide-1 (HNP-1) in circulating cells, whereas latent TB infected donors showed no differences when compared with purified pr...

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Bibliographic Details
Main Authors: Julio E Castañeda-Delgado, Alberto Cervantes-Villagrana, Carmen J Serrano-Escobedo, Isabel Frausto-Lujan, Cesar Rivas-Santiago, Jose A Enciso-Moreno, Bruno Rivas-Santiago
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2014-06-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
tuberculosis
latent infection
antimicrobial peptides
tuberculin skin test
QuantiFERON
biomarker
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762014000300330&lng=en&tlng=en

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