Structural and Biochemical Characterization of Botulinum Neurotoxin Subtype B2 Binding to Its Receptors

Structural and Biochemical Characterization of Botulinum Neurotoxin Subtype B2 Binding to Its Receptors

Botulinum neurotoxins (BoNTs) can be used therapeutically to treat a wide range of neuromuscular and neurological conditions. A collection of natural BoNT variants exists which can be classified into serologically distinct serotypes (BoNT/B), and further divided into subtypes (BoNT/B1, B2, …). BoNT...

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Bibliographic Details
Main Authors: Jonathan R. Davies, Geoffrey Masuyer, Pål Stenmark
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Toxins
Subjects:
<i>Clostridium botulinum</i>
botulism
botulinum neurotoxin
BoNT/B
synaptotagmin
ganglioside
Online Access:https://www.mdpi.com/2072-6651/12/9/603

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