Cell-Type Specific Determinants of NRAMP1 Expression in Professional Phagocytes

Cell-Type Specific Determinants of NRAMP1 Expression in Professional Phagocytes

The Natural resistance-associated macrophage protein 1 (Nramp1 or Solute carrier 11 member 1, Slc11a1) transports divalent metals across the membrane of late endosomes and lysosomes in professional phagocytes. Nramp1 represents an ancient eukaryotic cell-autonomous defense whereas the gene duplicati...

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Bibliographic Details
Main Author: Mathieu F. M. Cellier
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:Biology
Subjects:
natural resistance-associated macrophage protein (Nramp)
SLC11A1
regulation of gene expression
myeloid differentiation
genetic variation
HL-60 cells
C/EBP&#946
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Online Access:http://www.mdpi.com/2079-7737/2/1/233

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