Role of GD3 Synthase ST8Sia I in Cancers

Role of GD3 Synthase ST8Sia I in Cancers

GD3 synthase controls the biosynthesis of complex gangliosides, bearing two or more sialic acid residues. Disialylated gangliosides GD3 and GD2 are tumor-associated carbohydrate antigens (TACA) in neuro–ectoderm-derived cancers, and are directly involved in cell malignant properties, i.e., migration...

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Bibliographic Details
Main Authors:	Angelina Kasprowicz, Groux-Degroote Sophie, Chann Lagadec, Philippe Delannoy
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Series:	Cancers
Subjects:	ganglioside GD3 synthase epithelial–mesenchymal transition transcriptional regulation
Online Access:	https://www.mdpi.com/2072-6694/14/5/1299

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