Case studies in physiology: Nocturnal cardiorespiratory adaptive differences between an Italian trekker and a Nepali guide
Abstract The cardiopulmonary system is a physiological cornerstone in the adaptive response to hypobaric hypoxia. Portable devices make it feasible nowadays to precisely assess the response to high altitude (HA) expeditions. In this study, we investigated breathing and arterial blood pressure respon...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-08-01
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| Series: | Physiological Reports |
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| Online Access: | https://doi.org/10.14814/phy2.14537 |
| _version_ | 1818838985093414912 |
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| author | Danilo Bondi Suwas Bhandari Vittore Verratti |
| author_facet | Danilo Bondi Suwas Bhandari Vittore Verratti |
| author_sort | Danilo Bondi |
| collection | DOAJ |
| description | Abstract The cardiopulmonary system is a physiological cornerstone in the adaptive response to hypobaric hypoxia. Portable devices make it feasible nowadays to precisely assess the response to high altitude (HA) expeditions. In this study, we investigated breathing and arterial blood pressure responses during a Himalayan trek from 665 m to 4,780 m altitude in a white European (Italian) sojourner and a native Nepali (Tamang) guide, both healthy males. Resting diurnal and nocturnal data were acquired by means of ambulatory blood pressure monitoring (ABPM) and sleep apnea monitoring. We found an increase in the mean diurnal arterial blood pressure. Nocturnal blood pressure dipping was confirmed at all altitudes. Oxygen saturation decreased at altitude, with its additional nocturnal fall. Sleep apneic episodes, present in the Italian only, increased with altitude. We conclude that the nocturnal, more than diurnal, cardiorespiratory function is affected by HA hypoxia. Further studies should address the role of ethnicity, medications, and sociodemographic factors in the cardiorespiratory responses to hypobaric hypoxia. |
| first_indexed | 2024-12-19T03:47:05Z |
| format | Article |
| id | doaj.art-04d389fcb1c8408f9845a09d6ddea9ed |
| institution | Directory Open Access Journal |
| issn | 2051-817X |
| language | English |
| last_indexed | 2024-12-19T03:47:05Z |
| publishDate | 2020-08-01 |
| publisher | Wiley |
| record_format | Article |
| series | Physiological Reports |
| spelling | doaj.art-04d389fcb1c8408f9845a09d6ddea9ed2022-12-21T20:37:06ZengWileyPhysiological Reports2051-817X2020-08-01816n/an/a10.14814/phy2.14537Case studies in physiology: Nocturnal cardiorespiratory adaptive differences between an Italian trekker and a Nepali guideDanilo Bondi0Suwas Bhandari1Vittore Verratti2Department of Neuroscience, Imaging and Clinical Sciences University “G. d’Annunzio” of Chieti – Pescara Chieti ItalyWenzhou Medical University Wenzhou ChinaDepartment of Psychological, Health and Territorial Sciences University “G. d’Annunzio” of Chieti – Pescara Chieti ItalyAbstract The cardiopulmonary system is a physiological cornerstone in the adaptive response to hypobaric hypoxia. Portable devices make it feasible nowadays to precisely assess the response to high altitude (HA) expeditions. In this study, we investigated breathing and arterial blood pressure responses during a Himalayan trek from 665 m to 4,780 m altitude in a white European (Italian) sojourner and a native Nepali (Tamang) guide, both healthy males. Resting diurnal and nocturnal data were acquired by means of ambulatory blood pressure monitoring (ABPM) and sleep apnea monitoring. We found an increase in the mean diurnal arterial blood pressure. Nocturnal blood pressure dipping was confirmed at all altitudes. Oxygen saturation decreased at altitude, with its additional nocturnal fall. Sleep apneic episodes, present in the Italian only, increased with altitude. We conclude that the nocturnal, more than diurnal, cardiorespiratory function is affected by HA hypoxia. Further studies should address the role of ethnicity, medications, and sociodemographic factors in the cardiorespiratory responses to hypobaric hypoxia.https://doi.org/10.14814/phy2.14537blood pressurebreathingHimalayashypobaric hypoxiaphysiological monitoringsleep |
| spellingShingle | Danilo Bondi Suwas Bhandari Vittore Verratti Case studies in physiology: Nocturnal cardiorespiratory adaptive differences between an Italian trekker and a Nepali guide Physiological Reports blood pressure breathing Himalayas hypobaric hypoxia physiological monitoring sleep |
| title | Case studies in physiology: Nocturnal cardiorespiratory adaptive differences between an Italian trekker and a Nepali guide |
| title_full | Case studies in physiology: Nocturnal cardiorespiratory adaptive differences between an Italian trekker and a Nepali guide |
| title_fullStr | Case studies in physiology: Nocturnal cardiorespiratory adaptive differences between an Italian trekker and a Nepali guide |
| title_full_unstemmed | Case studies in physiology: Nocturnal cardiorespiratory adaptive differences between an Italian trekker and a Nepali guide |
| title_short | Case studies in physiology: Nocturnal cardiorespiratory adaptive differences between an Italian trekker and a Nepali guide |
| title_sort | case studies in physiology nocturnal cardiorespiratory adaptive differences between an italian trekker and a nepali guide |
| topic | blood pressure breathing Himalayas hypobaric hypoxia physiological monitoring sleep |
| url | https://doi.org/10.14814/phy2.14537 |
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