Drug Repurposing Approaches towards Defeating Multidrug-Resistant Gram-Negative Pathogens: Novel Polymyxin/Non-Antibiotic Combinations

Drug Repurposing Approaches towards Defeating Multidrug-Resistant Gram-Negative Pathogens: Novel Polymyxin/Non-Antibiotic Combinations

Multidrug-resistant (MDR) Gram-negative pathogens remain an unmet public health threat. In recent times, increased rates of resistance have been reported not only to commonly used antibiotics, but also to the last-resort antibiotics, such as polymyxins. More worryingly, despite the current trends in...

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Bibliographic Details
Main Authors: Augustine Koh Jing Jie, Maytham Hussein, Gauri G. Rao, Jian Li, Tony Velkov
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pathogens
Subjects:
antimicrobial resistance
polymyxins
drug repurposing
non-antibiotic agents
Online Access:https://www.mdpi.com/2076-0817/11/12/1420

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