Systemic analysis of urinary stones from the Northern, Eastern, Central, Southern and Southwest China by a multi-center study
Abstract Background To provide some basis for the prevention of urinary stones in general population, we did a systemic analysis of urinary stones from Northern, Eastern, Central, Southern and Southwest China by a multi-center study. Methods A total of 11,157 urinary stones from Northern, Eastern, C...
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| Language: | English |
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BMC
2018-12-01
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| Series: | BMC Urology |
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| Online Access: | http://link.springer.com/article/10.1186/s12894-018-0428-2 |
| _version_ | 1828385861729779712 |
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| author | Rui-hong Ma Xiao-bing Luo Qin Li Hai-qiang Zhong |
| author_facet | Rui-hong Ma Xiao-bing Luo Qin Li Hai-qiang Zhong |
| author_sort | Rui-hong Ma |
| collection | DOAJ |
| description | Abstract Background To provide some basis for the prevention of urinary stones in general population, we did a systemic analysis of urinary stones from Northern, Eastern, Central, Southern and Southwest China by a multi-center study. Methods A total of 11,157 urinary stones from Northern, Eastern, Central, Southern and Southwest China were obtained and analyzed by Fourier transform infrared spectroscopy. Combined with scanning electron microscopy and X-ray energy spectrometer, urinary stones were classified into different types. Furthermore, the correlation between stone types and clinical characteristics, as well as their regional distribution were elucidated. Results Calcium oxalate stones were the most common type in each region, followed by calcium oxalate-calcium phosphate mixed stones, uric acid stones and calcium phosphate stones. The distribution of calcium oxalate stones were highest prevalence in Southwest China (67.9%, P < 0.05), followed by Eastern and Northern China. Anhydrous uric acid stones, with a constituent ratio of 19.3% in Southern China, and 13.7% in Central China, were significantly higher than that in other regions (P < 0.05). Elements analysis indicated varieties among stone types as well as distribution regions. Moreover, the clinical characteristics were highly correlated with stone types and anatomical locations but not their distribution regions. Conclusions The material and elements composition of urinary stones among different regions showed some varieties. Calcium oxalate stone has the highest constituent ratio in Southwest China, while anhydrous uric acid stone has the highest constituent ratio in Southern China. Moreover, the clinical characteristics were highly correlated with stone types and anatomical locations but not their distribution regions. |
| first_indexed | 2024-12-10T05:28:19Z |
| format | Article |
| id | doaj.art-04d88c41e284457fb8c8efa040d30414 |
| institution | Directory Open Access Journal |
| issn | 1471-2490 |
| language | English |
| last_indexed | 2024-12-10T05:28:19Z |
| publishDate | 2018-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Urology |
| spelling | doaj.art-04d88c41e284457fb8c8efa040d304142022-12-22T02:00:38ZengBMCBMC Urology1471-24902018-12-0118111010.1186/s12894-018-0428-2Systemic analysis of urinary stones from the Northern, Eastern, Central, Southern and Southwest China by a multi-center studyRui-hong Ma0Xiao-bing Luo1Qin Li2Hai-qiang Zhong3The Department of Clinical Laboratory, The Sixth People’s Hospital of NanshaThe Department of Clinical Laboratory, The Sixth People’s Hospital of NanshaThe Department of Pulmonary, Critical Care and Sleep, Yale School of MedicineThe Department of Clinical Laboratory, The Sixth People’s Hospital of NanshaAbstract Background To provide some basis for the prevention of urinary stones in general population, we did a systemic analysis of urinary stones from Northern, Eastern, Central, Southern and Southwest China by a multi-center study. Methods A total of 11,157 urinary stones from Northern, Eastern, Central, Southern and Southwest China were obtained and analyzed by Fourier transform infrared spectroscopy. Combined with scanning electron microscopy and X-ray energy spectrometer, urinary stones were classified into different types. Furthermore, the correlation between stone types and clinical characteristics, as well as their regional distribution were elucidated. Results Calcium oxalate stones were the most common type in each region, followed by calcium oxalate-calcium phosphate mixed stones, uric acid stones and calcium phosphate stones. The distribution of calcium oxalate stones were highest prevalence in Southwest China (67.9%, P < 0.05), followed by Eastern and Northern China. Anhydrous uric acid stones, with a constituent ratio of 19.3% in Southern China, and 13.7% in Central China, were significantly higher than that in other regions (P < 0.05). Elements analysis indicated varieties among stone types as well as distribution regions. Moreover, the clinical characteristics were highly correlated with stone types and anatomical locations but not their distribution regions. Conclusions The material and elements composition of urinary stones among different regions showed some varieties. Calcium oxalate stone has the highest constituent ratio in Southwest China, while anhydrous uric acid stone has the highest constituent ratio in Southern China. Moreover, the clinical characteristics were highly correlated with stone types and anatomical locations but not their distribution regions.http://link.springer.com/article/10.1186/s12894-018-0428-2Urinary stonesFourier transform infrared spectroscopyScanning electron microscopyX-ray energy spectrometerCalcium oxalate stonesUric acid stones |
| spellingShingle | Rui-hong Ma Xiao-bing Luo Qin Li Hai-qiang Zhong Systemic analysis of urinary stones from the Northern, Eastern, Central, Southern and Southwest China by a multi-center study BMC Urology Urinary stones Fourier transform infrared spectroscopy Scanning electron microscopy X-ray energy spectrometer Calcium oxalate stones Uric acid stones |
| title | Systemic analysis of urinary stones from the Northern, Eastern, Central, Southern and Southwest China by a multi-center study |
| title_full | Systemic analysis of urinary stones from the Northern, Eastern, Central, Southern and Southwest China by a multi-center study |
| title_fullStr | Systemic analysis of urinary stones from the Northern, Eastern, Central, Southern and Southwest China by a multi-center study |
| title_full_unstemmed | Systemic analysis of urinary stones from the Northern, Eastern, Central, Southern and Southwest China by a multi-center study |
| title_short | Systemic analysis of urinary stones from the Northern, Eastern, Central, Southern and Southwest China by a multi-center study |
| title_sort | systemic analysis of urinary stones from the northern eastern central southern and southwest china by a multi center study |
| topic | Urinary stones Fourier transform infrared spectroscopy Scanning electron microscopy X-ray energy spectrometer Calcium oxalate stones Uric acid stones |
| url | http://link.springer.com/article/10.1186/s12894-018-0428-2 |
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